Title:
NERVOUS SYSTEM DELIVERY ENHANCER
Document Type and Number:
WIPO Patent Application WO/2024/071362
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a new method for improving the delivery efficiency of a drug such as a nucleic acid drug to the nervous system. Provided is a delivery enhancer for enhancing the delivery of a drug to the central nervous system and/or peripheral nervous system, the delivery enhancer comprising an aquaporin-4 function enhancer or an aquaporin-4 function modifier.
Inventors:
YOKOTA TAKANORI (JP)
YOSHIOKA KOTARO (JP)
NAGATA TETSUYA (JP)
HARA RINTARO (JP)
IGARASHI HIRONAKA (JP)
YOSHIOKA KOTARO (JP)
NAGATA TETSUYA (JP)
HARA RINTARO (JP)
IGARASHI HIRONAKA (JP)
Application Number:
PCT/JP2023/035565
Publication Date:
April 04, 2024
Filing Date:
September 29, 2023
Export Citation:
Assignee:
UNIV NAT CORP TOKYO MEDICAL & DENTAL (JP)
UNIV NIIGATA (JP)
UNIV NIIGATA (JP)
International Classes:
A61K47/22; A61K9/10; A61K9/127; A61K31/7105; A61K45/00; A61K47/60; A61K47/62; A61K47/68; A61K47/69; A61K48/00; A61P25/00; A61P25/02; C07D213/76; C07K14/00; C07K16/00; C12N15/11; C12N15/113; C12N15/115; C12N15/63
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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