Title:
METHOD, COLUMN, AND DEVICE FOR ANALYZING ORGANIC ACID BY MASS SPECTROMETRY
Document Type and Number:
WIPO Patent Application WO/2015/170516
Kind Code:
A1
Abstract:
[Problem] To provide a method and a column for analysis by mass spectrometry with a liquid chromatograph/mass spectrometer in which an organic acid is retained, separated, and eluted without adding any nonvolatile substance to the mobile phase nor restricting the proportion of a water-soluble organic solvent, and can be detected with high sensitivity.
[Solution] This method for analyzing an organic acid by mass spectrometry with a liquid chromatograph/mass spectrometer is a method in which a column packed with a hydrophilic polymer having anion-exchange groups is used and a water-soluble organic solvent/water mixed solution is used as the mobile phase. The column, which is for use in liquid chromatography for organic acids, was obtained by packing a hydrophilic polymer having anion-exchange groups into a liquid-chromatographic housing constituted of a polyetheretherketone (PEEK) resin.
Inventors:
KONDO HIDEYUKI (JP)
SASUGA JUNJI (JP)
SHUKUYA TAKAYUKI (JP)
SASUGA JUNJI (JP)
SHUKUYA TAKAYUKI (JP)
Application Number:
PCT/JP2015/058195
Publication Date:
November 12, 2015
Filing Date:
March 19, 2015
Export Citation:
Assignee:
SHOWA DENKO KK (JP)
International Classes:
G01N30/72; G01N27/62; G01N30/02; G01N30/26; G01N30/56; G01N30/88
Foreign References:
| JP2001040032A | 2001-02-13 | |||
| JP2008096258A | 2008-04-24 | |||
| JP2004125453A | 2004-04-22 |
Other References:
JUNJI SASUGA ET AL.: "Multi-mode Column Shodex RSpak JJ-50 2D o Mochiita LC/MS ni yoru Haloacetic Acid Oyobi Kaensosan no Kokando Bunseki", DAI 22 KAI SYMPOSIUM ON ENVIRONMENTAL CHEMISTRY PROGRAM AND ABSTRACTS, 2013, pages 1PC - 25, XP008185603
See also references of EP 3141894A4
See also references of EP 3141894A4
Attorney, Agent or Firm:
SSINPAT PATENT FIRM (JP)
Patent business corporation SSINPAT (JP)
Patent business corporation SSINPAT (JP)
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