Title:
METHOD FOR CONSTRUCTING SEQUENCING LIBRARY BASED ON BLOOD SAMPLE AND USAGE THEREOF IN DETERMINING FETAL GENETIC ABNORMALITY
Document Type and Number:
WIPO Patent Application WO/2016/037389
Kind Code:
A1
Abstract:
A method of preparing a sequencing library based on a blood sample, a method of sequencing a nucleic acid, a method for determining a fetal genetic abnormality of a chromosomal aneuploidy in a sample obtained from a pregnant female subject, an apparatus to prepare a sequencing library based on a blood sample, an assembly to sequence a nucleic acid, and a system for determining a fetal genetic abnormality of a chromosomal aneuploidy in a sample obtained from a pregnant female subject are provided.
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Inventors:
ZHANG YANYAN (CN)
CHEN FANG (CN)
JIANG HUI (CN)
GUO YULAI (CN)
ZENG PENG (CN)
XU XUN (CN)
YANG HUANMING (CN)
BALLINGER DENNIS G (US)
BASHKIROV VLADIMIR I (US)
SETHI HIMANSHU (US)
CHEN FANG (CN)
JIANG HUI (CN)
GUO YULAI (CN)
ZENG PENG (CN)
XU XUN (CN)
YANG HUANMING (CN)
BALLINGER DENNIS G (US)
BASHKIROV VLADIMIR I (US)
SETHI HIMANSHU (US)
Application Number:
PCT/CN2014/087589
Publication Date:
March 17, 2016
Filing Date:
September 26, 2014
Export Citation:
Assignee:
BGI GENOMICS CO LTD (CN)
International Classes:
C12N15/10; C40B50/06; C12Q1/68; C40B40/08
Domestic Patent References:
| WO2008070375A2 | 2008-06-12 | |||
| WO2009061840A1 | 2009-05-14 | |||
| WO2008015396A2 | 2008-02-07 | |||
| WO2010030683A1 | 2010-03-18 | |||
| WO2013191775A2 | 2013-12-27 | |||
| WO2013112923A1 | 2013-08-01 | |||
| WO2007140417A2 | 2007-12-06 |
Foreign References:
| US20110281736A1 | 2011-11-17 | |||
| US20100105052A1 | 2010-04-29 | |||
| US20100069263A1 | 2010-03-18 |
Other References:
UKAI, HIDEKI ET AL.: "A new technique to prevent self-ligation of DNA", JOURNAL OF BIOTECHNOLOGY, vol. 97, no. 3, 28 August 2002 (2002-08-28), pages 233 - 242, XP002471622, DOI: doi:10.1016/S0168-1656(02)00107-4
See also references of EP 3191630A4
See also references of EP 3191630A4
Attorney, Agent or Firm:
TSINGYIHUA INTELLECTUAL PROPERTY LLC (Trade Building Zhaolanyuan, Tsinghua University, Qinghuayuan, Haidian District, Beijing 4, CN)
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