Title:
METHOD FOR DETERMINING ORIGIN OF HUMAN GENOMIC DNA OF 100 pg OR LESS THEREFROM, METHOD FOR PERSONAL IDENTIFICATION, AND METHOD FOR ANALYZING DEGREE OF ENGRAFTMENT OF HEMATOPOIETIC STEM CELL
Document Type and Number:
WIPO Patent Application WO/2018/061638
Kind Code:
A1
Abstract:
Provided are: a method for determining the origin of human genomic DNA of 100 pg or less by uniformly amplifying the human genomic DNA of 100 pg or less; a method for personal identification; and a method for analyzing the degree of engraftment of a hematopoietic stem cell.
Inventors:
INOUE YUKI (JP)
TSUJIMOTO TAKAYUKI (JP)
NAKATANI TOSHIYUKI (JP)
TSUJIMOTO TAKAYUKI (JP)
NAKATANI TOSHIYUKI (JP)
Application Number:
PCT/JP2017/031764
Publication Date:
April 05, 2018
Filing Date:
September 04, 2017
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
C12Q1/68; C12N15/09
Domestic Patent References:
| WO2008004691A1 | 2008-01-10 | |||
| WO2016159132A1 | 2016-10-06 | |||
| WO2016159111A1 | 2016-10-06 | |||
| WO2008004691A1 | 2008-01-10 |
Foreign References:
| JP2011062085A | 2011-03-31 | |||
| JP2009508500A | 2009-03-05 |
Other References:
RACHLIN, J. ET AL.: "Computational tradeoffs in multiplex PCR assay design for SNP genotyping", BMC GENOMICS, vol. 6, no. 102, 2005, pages 1 - 11, XP021002191, ISSN: 1471-2164, DOI: 10.1186/1471-2164-6-102
LI, H. ET AL.: "Fast and accurate short read alignment with Burrows-Wheeler transform", BIOINFORMATICS, vol. 25, no. 14, 2009, pages 1754 - 1760, XP055287430, DOI: doi:10.1093/bioinformatics/btp324
LI, H. ET AL.: "Fast and accurate long-read alignment with Burrows-Wheeler transform", BIOINFORMATICS, vol. 26, no. 5, 2010, pages 589 - 595
LI, HENG ET AL.: "The Sequence Alignment / Map format and SAMtools", BIOINFORMATICS, vol. 25, no. 16, 2009, pages 2078 - 2079, XP055229864, DOI: doi:10.1093/bioinformatics/btp352
QUINLAN, A. R. ET AL.: "BEDtools: a flexible suite of utilities for comparing genomic features", BIOINFORMATICS, vol. 26, no. 6, 2010, pages 841 - 842, XP055307411, DOI: doi:10.1093/bioinformatics/btq033
ALTSCHUL, S. A. ET AL.: "Basic Local Alignment Search Tool", JOURNAL OF MOLECULAR BIOLOGY, vol. 215, October 1990 (1990-10-01), pages 403 - 410, XP002949123, DOI: doi:10.1006/jmbi.1990.9999
PEARSON, W. R. ET AL.: "Proceedings of the National Academy of Sciences of the United States of America", vol. 85, April 1988, NATIONAL ACADEMY OF SCIENCES, article "Improved tools for biological sequence comparison", pages: 2444 - 2448
See also references of EP 3521444A4
LI, H. ET AL.: "Fast and accurate short read alignment with Burrows-Wheeler transform", BIOINFORMATICS, vol. 25, no. 14, 2009, pages 1754 - 1760, XP055287430, DOI: doi:10.1093/bioinformatics/btp324
LI, H. ET AL.: "Fast and accurate long-read alignment with Burrows-Wheeler transform", BIOINFORMATICS, vol. 26, no. 5, 2010, pages 589 - 595
LI, HENG ET AL.: "The Sequence Alignment / Map format and SAMtools", BIOINFORMATICS, vol. 25, no. 16, 2009, pages 2078 - 2079, XP055229864, DOI: doi:10.1093/bioinformatics/btp352
QUINLAN, A. R. ET AL.: "BEDtools: a flexible suite of utilities for comparing genomic features", BIOINFORMATICS, vol. 26, no. 6, 2010, pages 841 - 842, XP055307411, DOI: doi:10.1093/bioinformatics/btq033
ALTSCHUL, S. A. ET AL.: "Basic Local Alignment Search Tool", JOURNAL OF MOLECULAR BIOLOGY, vol. 215, October 1990 (1990-10-01), pages 403 - 410, XP002949123, DOI: doi:10.1006/jmbi.1990.9999
PEARSON, W. R. ET AL.: "Proceedings of the National Academy of Sciences of the United States of America", vol. 85, April 1988, NATIONAL ACADEMY OF SCIENCES, article "Improved tools for biological sequence comparison", pages: 2444 - 2448
See also references of EP 3521444A4
Attorney, Agent or Firm:
WATANABE Mochitoshi et al. (JP)
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