Title:
METHOD AND DEVICE FOR ENCAPSULATING CELL IN LIQUID DROPLET FOR SINGLE-CELL ANALYSIS
Document Type and Number:
WIPO Patent Application WO/2018/212603
Kind Code:
A1
Abstract:
Disclosed are a method and a device for encapsulating a cell in a liquid droplet for single-cell analysis or a method and a device for forming a liquid droplet for single-cell analysis. The method and the device according to one aspect use an inertial ordering effect, thereby increasing the rate at which a single cell is encapsulated in a single liquid droplet and the yield at which liquid droplets are produced.
Inventors:
PARK WOONG-YANG (KR)
MOON HUI-SUNG (KR)
KIM SHIN-HYUN (KR)
JE KWANGHWI (KR)
MOON HUI-SUNG (KR)
KIM SHIN-HYUN (KR)
JE KWANGHWI (KR)
Application Number:
PCT/KR2018/005646
Publication Date:
November 22, 2018
Filing Date:
May 17, 2018
Export Citation:
Assignee:
SAMSUNG LIFE PUBLIC WELFARE FOUNDATION (KR)
International Classes:
C12Q1/6869; B01L3/00; C12Q1/6806
Domestic Patent References:
| WO2016040476A1 | 2016-03-17 |
Foreign References:
| US20170128940A1 | 2017-05-11 | |||
| US20150355096A1 | 2015-12-10 | |||
| US20110223314A1 | 2011-09-15 |
Other References:
XUE, CHUNDONG: "Lateral migration of dual droplet trains in a double spiral microchannel", SCIENCE CHINA PHYSICS, MECHANICS & ASTRONOMY, vol. 59, no. 7, 674711, 17 May 2016 (2016-05-17), pages 1 - 10, XP035690473
MOON, HUI-SUNG: "Inertial-ordering-assisted droplet microfluidics for high-throughput single- cell RNA-sequencing", LAB ON A CHIP, vol. 18, no. 5, 31 January 2018 (2018-01-31), pages 775 - 784, XP055612771
MOON, HUI-SUNG: "Inertial-ordering-assisted droplet microfluidics for high-throughput single- cell RNA-sequencing", LAB ON A CHIP, vol. 18, no. 5, 31 January 2018 (2018-01-31), pages 775 - 784, XP055612771
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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