Title:
METHOD AND DEVICE FOR PRODUCING COMPRESSION COATED TABLETS
Document Type and Number:
WIPO Patent Application WO2003000485
Kind Code:
B1
Abstract:
A method is disclosed for producing coated compressed tablets, using at least one upper punch. The upper punch can be a single punch with a hollow shaft (1) containing a movable rod (3) with a tip (4) that is extended or retracted as the rod moves within the shaft. Alternatively, two solid upper punches are used, one with an extended tip and the other with a retracted tip. An upper punch with an extended tip is designed to produce cup-shaped compacts of excipient and/or polymeric tablet coating material, when inserted into the die. Core material is inserted into each cup. Additional coating material is then placed on top of the cup and core, within the die, and compressed with an upper punch with a retracted tip. The method and device of the present invention enables one to produce tablets from poorly compactable substances.
Inventors:
HARIHARAN MADHUSUDAN (US)
GUPTA VISHAL K (US)
NOACK ROBERT M (US)
GREN TORKEL (SE)
GUPTA VISHAL K (US)
NOACK ROBERT M (US)
GREN TORKEL (SE)
Application Number:
PCT/US2002/020196
Publication Date:
May 21, 2004
Filing Date:
June 25, 2002
Export Citation:
Assignee:
PHARMACIA CORP (US)
HARIHARAN MADHUSUDAN (US)
GUPTA VISHAL K (US)
NOACK ROBERT M (US)
GREN TORKEL (SE)
HARIHARAN MADHUSUDAN (US)
GUPTA VISHAL K (US)
NOACK ROBERT M (US)
GREN TORKEL (SE)
International Classes:
A61J3/10; A61K47/02; A61K9/24; A61K47/06; A61K47/10; A61K47/12; A61K47/14; A61K47/30; A61K47/32; A61K47/34; A61K47/36; A61K47/38; B30B11/02; B30B11/08; B30B11/34; B30B15/06; A61J3/00; (IPC1-7): B30B11/34; B30B11/08; A61J3/10
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