Title:
METHOD FOR DIAGNOSING PATHOLOGY IN BIOLOGICAL SAMPLES
Document Type and Number:
WIPO Patent Application WO2002046722
Kind Code:
A9
Abstract:
A method and system for diagnosing pathology, such as carcinoma, in a biological sample identifies presence of pathology based on the existence of an infrared markers in the extracellular material, rather than cells, in the biological sample. In the case of breast cancer diagnosis, an effective marker is a baseline slope of a 1280 cm-1 band in the infrared spectra of connective tissue, with normal biopsy samples exhibiting a positive slope and cancerous samples showing a relatively flat baseline. Infrared spectroscopy, both microscopic and macroscopic, may be used to identify a sample region containing extracellular material and to collect infrared absorbance data, from which the existence of the pathology marker is determined.
Inventors:
MARCOTT CURTIS ALLEN
DUKOR DR RINA K
DUKOR DR RINA K
Application Number:
PCT/US2001/046933
Publication Date:
November 06, 2003
Filing Date:
December 05, 2001
Export Citation:
Assignee:
PROCTER & GAMBLE (US)
VYSIS INC (US)
VYSIS INC (US)
International Classes:
G01N21/27; G01N21/35; G01N33/483; G01N33/574; G01N21/49; (IPC1-7): G01N21/35; G01N33/487
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