Title:
METHOD FOR MAKING HYDROXY-25-ENE-VITAMIN D COMPOUNDS
Document Type and Number:
WIPO Patent Application WO1999061417
Kind Code:
A3
Abstract:
The present invention provides a method for preparing a novel class of vitamin D compounds in which the C-25 or equivalent position has a double bond. In addition, the side chain is optionally extended by one or two methylene or methyne groups. The compounds prepared by the method of the present invention are of value as prodrugs for active 1 alpha , 24-dihydroxylated vitamin D compounds.
Inventors:
WYNBERG HANS (NL)
VRIES TON (NL)
POUWER KEES (NL)
VRIES TON (NL)
POUWER KEES (NL)
Application Number:
PCT/US1999/011950
Publication Date:
January 13, 2000
Filing Date:
May 28, 1999
Export Citation:
Assignee:
BONE CARE INT INC (US)
WYNBERG HANS (NL)
VRIES TON (NL)
POUWER KEES (NL)
WYNBERG HANS (NL)
VRIES TON (NL)
POUWER KEES (NL)
International Classes:
A61K31/59; C07C401/00; C07C403/00; C07C; (IPC1-7): C07C401/00
Domestic Patent References:
| WO1992012165A1 | 1992-07-23 |
Foreign References:
| US4225596A | 1980-09-30 | |||
| US5030772A | 1991-07-09 |
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