Title:
METHOD FOR MEASUREMENT OF ABILITY OF INDUCING ANTIGEN-SPECIFIC T CELLS
Document Type and Number:
WIPO Patent Application WO/2011/024482
Kind Code:
A1
Abstract:
A method for preparing antigen-specific T cells for use in the methods for preventing and treating cancer and infectious diseases utilizing cellular immunity systems; a method for measuring the antigen-specific CTLs-inducing ability of mammal-derived lymphocytes; an antigenic substance for use in the prevention or treatment of diseases associated with HPV16 infection; and a method for preventing or treating diseases associated with HPV16 infection, which comprises administering an antigenic substance or CTLs to a patient.
Inventors:
TORIGOE TOSHIHIKO (JP)
HIROHASHI YOSHIHIKO (JP)
MIZUUCHI MASAHITO (JP)
SATOH NORIYUKI (JP)
SUZUKI SATOSHI (JP)
SHIMIZU YOSHITAKA (JP)
SATOH YUICHIRO (JP)
HIROHASHI YOSHIHIKO (JP)
MIZUUCHI MASAHITO (JP)
SATOH NORIYUKI (JP)
SUZUKI SATOSHI (JP)
SHIMIZU YOSHITAKA (JP)
SATOH YUICHIRO (JP)
Application Number:
PCT/JP2010/005326
Publication Date:
March 03, 2011
Filing Date:
August 30, 2010
Export Citation:
Assignee:
BIOMEDCORE INC (JP)
UNIV SAPPORO MEDICAL (JP)
TORIGOE TOSHIHIKO (JP)
HIROHASHI YOSHIHIKO (JP)
MIZUUCHI MASAHITO (JP)
SATOH NORIYUKI (JP)
SUZUKI SATOSHI (JP)
SHIMIZU YOSHITAKA (JP)
SATOH YUICHIRO (JP)
UNIV SAPPORO MEDICAL (JP)
TORIGOE TOSHIHIKO (JP)
HIROHASHI YOSHIHIKO (JP)
MIZUUCHI MASAHITO (JP)
SATOH NORIYUKI (JP)
SUZUKI SATOSHI (JP)
SHIMIZU YOSHITAKA (JP)
SATOH YUICHIRO (JP)
International Classes:
C12N5/0783; A61K35/26; A61P31/04; A61P31/12; A61P31/14; A61P31/18; A61P31/20; A61P35/00; A61P35/02; C12N5/10; C12N15/09; C12Q1/04; G01N33/53; G01N33/544; C07K7/06; C07K7/08
Domestic Patent References:
| WO2005089164A2 | 2005-09-29 | |||
| WO2006104199A1 | 2006-10-05 |
Foreign References:
| JP2005504733A | 2005-02-17 | |||
| JP2006511221A | 2006-04-06 |
Other References:
TSUKUI T. ET AL: "Interleukin 2 production in vitro by peripheral lymphocytes in response to human papillomavirus-derived peptides: correlation with cervical pathology", CANCER RES., vol. 56, no. 17, 1996, pages 3967 - 3974, XP002149977
MURAKAMI M. ET AL: "Induction of specific CD8+ T-lymphocyte responses using a human papillomavirus-16 E6/E7 fusion protein and autologous dendritic cells", CANCER RES., vol. 59, no. 6, 1999, pages 1184 - 1187, XP002238464, DOI: doi:10.1016/S0065-230X(08)61025-8
TETSUHIRO TSURUMA ET AL: "Survivin-2B Peptide ni yoru Gan Peptide Vaccine Ryoho", JAPANESE JOURNAL OF CANCER AND CHEMOTHERAPY, vol. 31, no. 11, 2004, pages 1634 - 1636
FUKASAWA M. ET AL: "Liposome oligomannose-coated with neoglycolipid, a new candidate for a safe adjuvant for induction of CD8+ cytotoxic T lymphocytes", FEBS LETT., vol. 441, no. 3, 1998, pages 353 - 356, XP004258962, DOI: doi:10.1016/S0014-5793(98)01577-4
HIROKI NABETA ET AL.: "Akusei Kotsu Nanbu Shuyo ni Taisuru Men'eki Ryoho no Kaihatsu: Shuyo Kogen no Dotei", THE HOKKAIDO JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY, vol. 47, no. 2, 2006, pages 18 - 21
HATTORI Y. ET AL: "Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice", BIOCHEM BIOPHYS RES COMMUN., vol. 317, no. 4, 2004, pages 992 - 999, XP004502867, DOI: doi:10.1016/j.bbrc.2004.03.141
MURAKAMI M. ET AL: "Induction of specific CD8+ T-lymphocyte responses using a human papillomavirus-16 E6/E7 fusion protein and autologous dendritic cells", CANCER RES., vol. 59, no. 6, 1999, pages 1184 - 1187, XP002238464, DOI: doi:10.1016/S0065-230X(08)61025-8
TETSUHIRO TSURUMA ET AL: "Survivin-2B Peptide ni yoru Gan Peptide Vaccine Ryoho", JAPANESE JOURNAL OF CANCER AND CHEMOTHERAPY, vol. 31, no. 11, 2004, pages 1634 - 1636
FUKASAWA M. ET AL: "Liposome oligomannose-coated with neoglycolipid, a new candidate for a safe adjuvant for induction of CD8+ cytotoxic T lymphocytes", FEBS LETT., vol. 441, no. 3, 1998, pages 353 - 356, XP004258962, DOI: doi:10.1016/S0014-5793(98)01577-4
HIROKI NABETA ET AL.: "Akusei Kotsu Nanbu Shuyo ni Taisuru Men'eki Ryoho no Kaihatsu: Shuyo Kogen no Dotei", THE HOKKAIDO JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY, vol. 47, no. 2, 2006, pages 18 - 21
HATTORI Y. ET AL: "Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice", BIOCHEM BIOPHYS RES COMMUN., vol. 317, no. 4, 2004, pages 992 - 999, XP004502867, DOI: doi:10.1016/j.bbrc.2004.03.141
Attorney, Agent or Firm:
HASEGAWA, Tomoko et al. (JP)
Tomoko Hasegawa (JP)
Tomoko Hasegawa (JP)
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