METHOD FOR MEASURING INTEGRITY OF UID NUCLEIC ACID SEQUENCE IN NUCLEIC ACID SEQUENCING ANALYSIS

Title:

METHOD FOR MEASURING INTEGRITY OF UID NUCLEIC ACID SEQUENCE IN NUCLEIC ACID SEQUENCING ANALYSIS

Document Type and Number:

WIPO Patent Application WO/2019/108014

Kind Code:

A1

Abstract:

Provided are a polynucleotide for measuring the integrity of UID and a method for measuring the integrity of UID in nucleic acid sequencing by using the same, the polynucleotide comprising: a first region including a UID nucleic acid sequence; a second region including a nucleic acid sequence having no homology with a reference genome; and a third region including a nucleic acid sequence having homology with the reference genome.

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Inventors:

CHUNG JONG SUK (KR)
PARK DONG HYUN (KR)
PARK WOONG YANG (KR)

Application Number:

PCT/KR2018/015086

Publication Date:

June 06, 2019

Filing Date:

November 30, 2018

Export Citation:

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Assignee:

SAMSUNG LIFE PUBLIC WELFARE FOUNDATION (KR)

International Classes:

C12Q1/6869; C12Q1/6806; G16B30/00

Foreign References:

US20160319345A1	2016-11-03
KR20160141680A	2016-12-09
US20170058340A1	2017-03-02
JP2017511121A	2017-04-20

Other References:

KOU, R. ET AL.: "Benefits and Challenges with Applying Unique Molecular Identifiers in Next Generation Sequencing to Detect Low Frequency Mutations", PLOS ONE, vol. 11, no. 1, 11 January 2016 (2016-01-11), pages e0146638, XP055469818

Attorney, Agent or Firm:

Y.P.LEE, MOCK & PARTNERS (KR)

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