Title:
METHOD FOR PREPARING LIFITEGRAST AND INTERMEDIATE COMPOUND OF LIFITEGRAST
Document Type and Number:
WIPO Patent Application WO/2023/040103
Kind Code:
A1
Abstract:
A method for preparing lifitegrast and an intermediate compound of lifitegrast. Specifically, disclosed are a method for synthesizing lifitegrast, a key intermediate for synthesizing lifitegrast, a solvate of lifitegrast, and a method for preparing lifitegrast by hydrolyzing the solvate under an alkaline condition.
Inventors:
WANG XIAWEI (CN)
ZHENG ZHIGUO (CN)
ZHENG ZHIGUO (CN)
Application Number:
PCT/CN2021/139695
Publication Date:
March 23, 2023
Filing Date:
December 20, 2021
Export Citation:
Assignee:
THE FIRST AFFILIATED HOSPITAL ZHEJIANG UNTVERSITY SCHOOL OF MEDICINE (CN)
ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN)
ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D405/06
Domestic Patent References:
| WO2021107514A2 | 2021-06-03 | |||
| WO2019097547A1 | 2019-05-23 | |||
| WO2019053607A1 | 2019-03-21 | |||
| WO2009139817A2 | 2009-11-19 | |||
| WO2011050175A1 | 2011-04-28 | |||
| WO2019096996A1 | 2019-05-23 | |||
| WO2019097547A1 | 2019-05-23 |
Foreign References:
| CN106995439A | 2017-08-01 |
Attorney, Agent or Firm:
ZHONGZI LAW OFFICE (CN)
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