Title:
METHOD FOR PREPARING SALVIANOLIC ACID A SALT
Document Type and Number:
WIPO Patent Application WO/2018/145622
Kind Code:
A1
Abstract:
Provided in the present invention is a method for preparing a salvianolic acid A salt, the preparation method being: dissolving salvianolic acid A in water, then adjusting the pH value to be 1.2-5.5 by using an aqueous solution of a basic substance, and collecting a precipitate, i.e., a salvianolic acid A salt; the present invention uses a method of adding a basic solution to a salvianolic acid A aqueous solution to increase the pH value and precipitate a salvianolic acid A salt, thereby preparing and obtaining a salvianolic acid A salt product which has strong stability, cannot be easily oxidized, has high purity and reduced impurities; said preparation method is efficient, simple and easy to implement, while being more suitable for industrial mass production, and being beneficial to the development and application of salvianolic acid A salt.
Inventors:
PAN YINGFENG (CN)
LING YIPING (CN)
LIU LI (CN)
FU LINGZHU (CN)
ZHU CHENG (CN)
ZHANG LI (CN)
ZHANG PING (CN)
LIU XIAOYUN (CN)
YING XUHUI (CN)
SHI LIREN (CN)
LING YIPING (CN)
LIU LI (CN)
FU LINGZHU (CN)
ZHU CHENG (CN)
ZHANG LI (CN)
ZHANG PING (CN)
LIU XIAOYUN (CN)
YING XUHUI (CN)
SHI LIREN (CN)
Application Number:
PCT/CN2018/075398
Publication Date:
August 16, 2018
Filing Date:
February 06, 2018
Export Citation:
Assignee:
CHIATAI QINGCHUNBAO PHARMACEUTICAL CO LTD (CN)
International Classes:
C07C51/41; C07C69/732
Foreign References:
| CN106748733A | 2017-05-31 | |||
| CN102432467A | 2012-05-02 | |||
| CN101361728A | 2009-02-11 | |||
| CN105523926A | 2016-04-27 |
Attorney, Agent or Firm:
TIANZHENG PATENT ATTORNEYS (CN)
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