Title:
QUINOLINE COMPOUND, PREPARATION METHOD AND MEDICAL USE THEREFOR
Document Type and Number:
WIPO Patent Application WO/2018/145621
Kind Code:
A1
Abstract:
The present invention relates to a quinoline compound, as well as a preparation method and medical use therefor. Specifically, the present invention relates to a novel quinoline compound represented by the general formula (I) and a method for preparing the same, as well as a use therefor as an inhibitor for a plurality of protein kinases, and a use in the prevention and/or treatment of cancer in particular; the definition of each group in the general formula (I) is the same as the definition in the description.
Inventors:
SI JUTONG (CN)
JIANG MEIFENG (CN)
LI JIAYAN (CN)
ZENG HAN (CN)
YANG HUABIN (CN)
JIANG MEIFENG (CN)
LI JIAYAN (CN)
ZENG HAN (CN)
YANG HUABIN (CN)
Application Number:
PCT/CN2018/075392
Publication Date:
August 16, 2018
Filing Date:
February 06, 2018
Export Citation:
Assignee:
ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN)
International Classes:
A61K31/47; C07D215/02; A61K31/4709; A61P35/00; C07D215/16; C07D401/12
Domestic Patent References:
| WO2018028591A1 | 2018-02-15 | |||
| WO2016161952A1 | 2016-10-13 |
Foreign References:
| CN1308310C | 2007-04-04 |
Other References:
KLUETER, S. ET AL.: "Displacement Assay for the Detection of Stabilizers of Inactive Kinase Conformations", JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, no. 1, 23 November 2009 (2009-11-23), ISSN: 0022-2623
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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