METHOD FOR PREPARING SURFACE COATING WITH REDUCED DEGRADATION RATE OF BIODEGRADABLE MAGNESIUM ALLOY VASCULAR STENT

Title:

METHOD FOR PREPARING SURFACE COATING WITH REDUCED DEGRADATION RATE OF BIODEGRADABLE MAGNESIUM ALLOY VASCULAR STENT

Document Type and Number:

WIPO Patent Application WO/2015/172664

Kind Code:

A1

Abstract:

Disclosed is a method for preparing a surface coating with a reduced degradation rate of a biodegradable magnesium alloy vascular stent, comprising firstly grafting a silane coupling agent to the surface of a magnesium alloy by dip coating, heat curing, and forming a silane coupling agent coating on the surface of the magnesium alloy; and then coating a polymer on the surface of the silane coupling agent coating by spin coating, and drying under vacuum to form a polymer coating. The polymer coating coated on the surface of the magnesium alloy and pretreated by a silane coupling agent can enhance the bonding force with the surface of the magnesium alloy vascular stent to suppress excessive degradation of the magnesium alloy matrix, and improve the biocompatibility of the vascular stent.

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Inventors:

XI TINGFEI (CN)
LIU JING (CN)
WANG MIN (CN)
ZHANG ZHIXIONG (CN)

Application Number:

PCT/CN2015/077943

Publication Date:

November 19, 2015

Filing Date:

April 30, 2015

Export Citation:

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Assignee:

XI TINGFEI (CN)

International Classes:

A61L31/10; A61L31/08

Domestic Patent References:

WO2007095393A2

2007-08-23

Foreign References:

CN102008751A	2011-04-13
CN102596274A	2012-07-18
US20110217351A1	2011-09-08
CN102657899A	2012-09-12
CN102912335A	2013-02-06
CN104189963A	2014-12-10

Other References: