Title:
METHOD FOR PRODUCING 4-CHLOROPYRIDINE-2-CARBOXYLIC ACID CHLORIDE
Document Type and Number:
WIPO Patent Application WO/2011/093256
Kind Code:
A1
Abstract:
Provided is a production method that is industrially advantageous in that it is possible to obtain, at a high purity and a high yield, 4-chloropyridine-2-carboxylic acid chloride, which is useful as an intermediate starting material for drugs, agricultural chemicals, and the like. 4-chloropyridine-2-carboxylic acid chloride is efficiently obtained at a high purity and a high yield by using bromine as a catalyst when a pyridine-2-carboxylic acid derivative or salt thereof is reacted with thionyl chloride.
Inventors:
HANGUI MASAHIKO (JP)
SUZUKI YOSHINOBU (JP)
SUZUKI YOSHINOBU (JP)
Application Number:
PCT/JP2011/051274
Publication Date:
August 04, 2011
Filing Date:
January 25, 2011
Export Citation:
Assignee:
DNP FINE CHEMICALS FUKUSHIMA CO LTD (JP)
HANGUI MASAHIKO (JP)
SUZUKI YOSHINOBU (JP)
HANGUI MASAHIKO (JP)
SUZUKI YOSHINOBU (JP)
International Classes:
C07D213/78
Foreign References:
| JP2007223937A | 2007-09-06 |
Other References:
SUNDBERG R.J. ET AL: "Improved procedures for preparation of 4-hydroxy-and 2-amino-4-methoxy- 2-aminopyridines", ORGANIC PREPARATIONS AND PROCEDURES INT., vol. 29, no. 1, 1997, pages 117 - 122
NORA DE SOUZA, M.V. ET AL.: "Ortho-directed lithiation studies of 4-chloropicolinanilide: introduction of functional groups at C-3 and their elaboration to chain extended derivatives via carbon-carbon bond formation", HETEROCYCLES, vol. 47, no. 2, 1998, pages 811 - 827, XP002313564
NORA DE SOUZA, M.V. ET AL.: "Ortho-directed lithiation studies of 4-chloropicolinanilide: introduction of functional groups at C-3 and their elaboration to chain extended derivatives via carbon-carbon bond formation", HETEROCYCLES, vol. 47, no. 2, 1998, pages 811 - 827, XP002313564
Attorney, Agent or Firm:
HIRAKI Yusuke et al. (JP)
Yusuke Hiraki (JP)
Yusuke Hiraki (JP)
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