METHOD FOR PRODUCING COMPOSITE CONTAINING AMORPHOUS CURCUMIN AND/OR ANALOGUE THEREOF

Title:

METHOD FOR PRODUCING COMPOSITE CONTAINING AMORPHOUS CURCUMIN AND/OR ANALOGUE THEREOF

Document Type and Number:

WIPO Patent Application WO/2016/010093

Kind Code:

A1

Abstract:

Provided is a method for easily producing a composite that contains amorphous curcumin and/or an analogue thereof in high concentration at low cost, said composite having a high content of curcumin and/or an analogue thereof and improved absorption of curcumin and/or an analogue thereof in the body by oral intake. A method for producing a composite of curcumin and/or an analogue thereof and hydroxypropyl methylcellulose and/or hydroxypropyl cellulose, said composite containing amorphous curcumin and/or an analogue thereof, which is characterized by comprising: a step for dissolving curcumin and/or an analogue thereof and hydroxypropyl methylcellulose and/or hydroxypropyl cellulose into an aqueous solution having a pH of 12 or more; and a step for decreasing the pH of the solution to 7 or less.

Inventors:

IMAIZUMI ATSUSHI (JP)
OZAWA HITOMI (JP)
SATO SO (JP)
TAKAHASHI TSUKASA (JP)
MATSUI TAKATO (JP)
MAKINO YUJI (JP)
KATO CHIEKO (JP)

Application Number:

PCT/JP2015/070318

Publication Date:

January 21, 2016

Filing Date:

July 15, 2015

Export Citation:

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Assignee:

THERAVALUES CORP (JP)

International Classes:

A61K31/12; A61K9/14; A61K47/38

Foreign References:

JP2014503470A	2014-02-13
JPH04502004A	1992-04-09
JP2011512346A	2011-04-21

Other References:

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 7, no. 4, 2012, pages 271 - 279
INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 453, 2013, pages 253 - 284

Attorney, Agent or Firm:

THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)

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