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Title:
METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2011/102444
Kind Code:
A1
Abstract:
Provided is a method for producing induced pluripotent stem cells that have a low potential for tumor formation and ensure a high induction efficiency. The method for producing induced pluripotent stem cells includes a step for introducing nucleic acid which accelerates expression of at least one gene selected from the group consisting of NANOG gene, SOX2 gene, OCT3/4 gene, KLF4 gene, LIN28 gene and c-MYC gene in somatic cells.

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JP2590885[Title of Invention] DNA Fragment
JP2001245673NEW POLYPEPTIDE
JPH0570496RECOMBINANT CHERRY SALMON GROWTH HORMONE, ITS STRUCTURAL GENE, RECOMBINANT PLASMID, BACTERIUM CONTAINING THE SAME PLASMID AND PRODUCTION OF GROWTH HORMONE OR PREGROWTH HORMONE OF THE SAME SALMON
Inventors:
MORI MASAKI (JP)
ISHII HIDESHI (JP)
MIYOSHI NORIKATSU (JP)
DOKI YUICHIRO (JP)
TANEMURA MASAHIRO (JP)
NAGAI KENICHI (JP)
HOSHINO HIROMITSU (JP)
OMURA YOSHIAKI (JP)
HARAGUCHI NAOTSUGU (JP)
MIYAZAKI SUSUMU (JP)
Application Number:
PCT/JP2011/053457
Publication Date:
August 25, 2011
Filing Date:
February 18, 2011
Export Citation:
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Assignee:
UNIV OSAKA (JP)
MORI MASAKI (JP)
ISHII HIDESHI (JP)
MIYOSHI NORIKATSU (JP)
DOKI YUICHIRO (JP)
TANEMURA MASAHIRO (JP)
NAGAI KENICHI (JP)
HOSHINO HIROMITSU (JP)
OMURA YOSHIAKI (JP)
HARAGUCHI NAOTSUGU (JP)
MIYAZAKI SUSUMU (JP)
International Classes:
C12N15/09; C12N5/10; C12Q1/02; C12Q1/68
Domestic Patent References:
WO2009075119A12009-06-18
WO2006025802A12006-03-09
WO2007069666A12007-06-21
Other References:
JUDSON R.L. ET AL.: "Embryonic stem cell- specific microRNAs promote induced pluripotency.", NATURE BIOTECHNOLOGY, vol. 27, no. 5, May 2009 (2009-05-01), pages 459 - 461, XP002577534, DOI: doi:10.1038/nbt.1535
MICHIYO KOYANAGI ET AL.: "Mouse Taisaibo no Shokika ni Kakawaru microRNA no Tansaku to sono Kino Kaiseki", BMB2007 (DAI 30 KAI THE MOLECULAR BIOLOGY SOCIETY OF JAPAN SOKAI - DAI 80 KAI ANNUAL MEETING OF THE JAPANESE BIOCHEMICAL SOCIETY GODO TAIKAI) KOEN YOSHISHU, 25 November 2007 (2007-11-25), pages 504
MICHIYO KOYANAGI ET AL.: "Mouse - Hito Taisaibo no iPS Saiboka ni Kakawaru microRNA no Tansaku to sono Kino Kaiseki", BMB2008 (DAI 31 KAI THE MOLECULAR BIOLOGY SOCIETY OF JAPAN SOKAI - DAI 81 KAI ANNUAL MEETING OF THE JAPANESE BIOCHEMICAL SOCIETY GODO TAIKAI) KOEN YOSHISHU, 20 November 2008 (2008-11-20), pages 295
See also references of EP 2537930A4
SCIENCE, vol. 322, 2008, pages 949 - 953
NUCLEIC ACID RESEARCH, vol. 36, 2008, pages D154 - D158
CELL, vol. 126, 2006, pages 663 - 676
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 107, 2010, pages 40 - 45
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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