Title:
METHOD FOR PRODUCING L-AMINO ACID
Document Type and Number:
WIPO Patent Application WO/2010/101053
Kind Code:
A1
Abstract:
Disclosed is a method for producing L-amino acid, wherein a bacterium, which belongs to the family Enterobacteriaceae and has an L-amino acid-producing ability, while being modified so as to have a reduced ribonuclease G activity, is cultured in a culture medium that contains ethanol as a carbon source, so that L-amino acid is produced and accumulated in a culture, and then the thus-produced L-amino acid is collected from the culture.
Inventors:
HAGIWARA YUSUKE (JP)
NAGAI YURI (JP)
NAGAI YURI (JP)
Application Number:
PCT/JP2010/052845
Publication Date:
September 10, 2010
Filing Date:
February 24, 2010
Export Citation:
Assignee:
AJINOMOTO KK (JP)
HAGIWARA YUSUKE (JP)
NAGAI YURI (JP)
HAGIWARA YUSUKE (JP)
NAGAI YURI (JP)
International Classes:
C12P13/08; C12N1/21; C12N15/09
Domestic Patent References:
| WO2008010565A2 | 2008-01-24 |
Other References:
LEE, K. ET AL.: "RNase G complementation of rne null mutation identifies functional interrelationships with RNase E in Escherichia coli.", MOL. MICROBIOL., vol. 43, no. 6, 2002, pages 1445 - 1456
OW, M. C. ET AL.: "RNase G of Escherichia coli exhibits only limited functional overlap with its essential homologue, RNase E.", MOL. MICROBIOL., vol. 49, no. 3, 2003, pages 607 - 622
WACHI, M. ET AL.: "A Novel RNase G Mutant That Is Defective in Degradation of adhE mRNA but Proficient in the Processing of 16S rRNA Precursor.", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 289, 2001, pages 1301 - 1306
UMITSUKI, G. ET AL.: "Involvement of RNase G in in vivo mRNA metabolism in Escherichia coli.", GENES TO CELLS, vol. 6, 2001, pages 403 - 410
OW, M. C. ET AL.: "RNase G of Escherichia coli exhibits only limited functional overlap with its essential homologue, RNase E.", MOL. MICROBIOL., vol. 49, no. 3, 2003, pages 607 - 622
WACHI, M. ET AL.: "A Novel RNase G Mutant That Is Defective in Degradation of adhE mRNA but Proficient in the Processing of 16S rRNA Precursor.", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 289, 2001, pages 1301 - 1306
UMITSUKI, G. ET AL.: "Involvement of RNase G in in vivo mRNA metabolism in Escherichia coli.", GENES TO CELLS, vol. 6, 2001, pages 403 - 410
Attorney, Agent or Firm:
KAWAGUCHI, Yoshiyuki et al. (JP)
Yoshiyuki Kawaguchi (JP)
Yoshiyuki Kawaguchi (JP)
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