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Patent Searching and Data


Title:
METHOD FOR PROVIDING DATA TO DIAGNOSE DEPRESSION
Document Type and Number:
WIPO Patent Application WO/2012/049864
Kind Code:
A1
Abstract:
The present invention relates to a method for providing data to diagnose depression, the method comprising measuring the serum concentration of two or more proteins selected from the group consisting of IL-2 receptor alpha, macrophage migration-inhibitory factor, adiponectin, and brain-derived neurotrophic factor.

Inventors:
ROKUTAN KAZUHITO
KAMEZAKI YOSHIKO
NAYA SHIN-ICHI
HIGA YUKIKO
SUGAI MUTSUMI
IKEDA MASAHIRO
HOSAKA YUMIKO
HIGUCHI KEIKO
KAMIZATO MAI
Application Number:
PCT/JP2011/053836
Publication Date:
April 19, 2012
Filing Date:
February 22, 2011
Export Citation:
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Assignee:
KATAKURA IND CO LTD (JP)
UNIV TOKUSHIMA (JP)
ROKUTAN KAZUHITO
KAMEZAKI YOSHIKO
NAYA SHIN-ICHI
HIGA YUKIKO
SUGAI MUTSUMI
IKEDA MASAHIRO
HOSAKA YUMIKO
HIGUCHI KEIKO
KAMIZATO MAI
International Classes:
G01N33/68; G01N33/53
Foreign References:
JP2008509409A2008-03-27
JP2002529706A2002-09-10
Other References:
M. MAES ET AL.: "Plasma soluble interleukin-2- receptor in depression: relationships to plasma neopterin and serum IL-2 concentrations and HPA-axis activity", EUROPEAN PSYCHIATRY, vol. 10, no. ISS.8, 1995, pages 397 - 403
TRIIN ELLER ET AL.: "Soluble interleukin-2 receptor and tumor necrosis factor levelsin depressed patients in Estonia", MEDICINA (KAUNAS), vol. 45, no. 12, 2009, pages 971 - 977
KATE M. EDWARDS ET AL.: "Elevated Macrophage Migration Inhibitory Factor (MIF) is associated with depressive symptoms, blunted cortisol reactivity to acute stress, and lowered morning cortisol", BRAIN, BEHAVIOR, AND IMMUNITY, vol. 24, no. ISS.7, 9 April 2010 (2010-04-09), pages 1202 - 1208
LEHTO S. M. ET AL.: "Serum adiponectin and resistin levels in major depressive disorder", ACTA PSYCHIATRICA SCANDINAVICA, vol. 121, no. ISS.3, March 2010 (2010-03-01), pages 209 - 215
KENJI HASHIMOTO: "No Yurai Shinkei Eiyo Inshi to Utsubyo", BRAIN SCIENCE AND MENTAL DISORDERS, vol. 20, no. 1, 2009, pages 55 - 60
TADANAO SHIMIZU ET AL.: "Macrophage Yuso Soshi Inshi (MIF) to sono Kino", ALLERGY-KA, vol. 15, no. 6, 2003, pages 459 - 463
Attorney, Agent or Firm:
TSUKUNI, HAJIME (JP)
Hajime Tsukuni (JP)
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Claims: