Title:
METHOD FOR PURIFYING FACTOR XIII
Document Type and Number:
WIPO Patent Application WO/2023/153878
Kind Code:
A1
Abstract:
Disclosed is a method of purifying factor XIII comprising (a) first salt precipitation, (b) heat treatment, and (c) second salt precipitation, in which factor XIII can be purified at high yield from a plasma sample or the like through a simple process, and factor XIII can be purified with high purity. In addition, since this method can be applied to large-scale industrial production, it is an economical and efficient purification method, and can be useful in the field of prevention and treatment of diseases associated with factor XIII deficiency.
Inventors:
BAN TAEHYUN (KR)
BANG EUN (KR)
SEO KANG YUN (KR)
JANG IL HA (KR)
KIM MIN-JUNG (KR)
BANG EUN (KR)
SEO KANG YUN (KR)
JANG IL HA (KR)
KIM MIN-JUNG (KR)
Application Number:
PCT/KR2023/002024
Publication Date:
August 17, 2023
Filing Date:
February 10, 2023
Export Citation:
Assignee:
GREEN CROSS CORP (KR)
International Classes:
C07K14/755; C07K1/18; C07K1/30; C07K1/34
Domestic Patent References:
| WO2011149472A1 | 2011-12-01 |
Foreign References:
| US5204447A | 1993-04-20 | |||
| US5981254A | 1999-11-09 | |||
| US20080207878A1 | 2008-08-28 |
Other References:
WANG WAN, LIU JIANBO, HAN YONG, HUANG WEI, WANG QUNJIE: "The most convenient and general approach for plasma sample clean-up: multifunction adsorption and supported liquid extraction", BIOANALYSIS, FUTURE SCIENCE, LONDON, UK, vol. 4, no. 3, 1 January 2012 (2012-01-01), London, UK , pages 223 - 225, XP009547947, ISSN: 1757-6180, DOI: 10.4155/bio.11.332
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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