Title:
METHOD FOR THE QUANTIFICATION OF FAECALIBACTERIUM PRAUSNITZII PHYLOGROUP I AND/OR PHYLOGROUP II MEMBERS AND THE USE THEREOF AS BIOMARKERS
Document Type and Number:
WIPO Patent Application WO/2017/025617
Kind Code:
A8
Abstract:
The present invention relates to a novel method for an accurate quantification in intestinal samples of Faecalibacterium prausnitzii phylogroup I members (PHGI) and/or Faecalibacterium prausnitzii phylogroup II members (PHGII). It further relates to a method for detecting intestinal diseases, including the screening, diagnosis, differential diagnosis, and/or monitoring of disease activity or progression in a human subject comprising determining the abundance of PHGI and/or PHGII in an intestinal sample from said subject. Moreover, it relates to a method for the prediction of the efficacy of a drug in the therapeutic treatment of an intestinal disease in a human subject comprising determining the abundance of PHGI and/or PHGII in an intestinal sample from said subject.
Inventors:
LÓPEZ SILES MIREIA (ES)
GARCÍA GIL LIBRADO JESÚS (ES)
ALDEGUER MANTÉ XAVIER (ES)
MARTÍNEZ MEDINA MARGARITA (ES)
GARCÍA GIL LIBRADO JESÚS (ES)
ALDEGUER MANTÉ XAVIER (ES)
MARTÍNEZ MEDINA MARGARITA (ES)
Application Number:
PCT/EP2016/069188
Publication Date:
July 27, 2017
Filing Date:
August 11, 2016
Export Citation:
Assignee:
UNIV GIRONA (ES)
FUND INST D'INVESTIGACIÓ BIOMÈDICA DE GIRONA DR JOSEP TRUETA (ES)
GOODGUT S L (ES)
FUND INST D'INVESTIGACIÓ BIOMÈDICA DE GIRONA DR JOSEP TRUETA (ES)
GOODGUT S L (ES)
International Classes:
C12Q1/68
Attorney, Agent or Firm:
HOFFMANN EITLE, S.L.U. (Edificio LimaPaseo de la Castellan, 140 Madrid, ES)
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