Title:
METHOD FOR REESTABLISHING PLURIPOTENT STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2016/052759
Kind Code:
A1
Abstract:
The present application pertains to a method for reestablishing stem cells having a chimera-forming capacity, and to cells obtained by said method. This method is a technique for improving stem cell quality by monoclonally replicating stem cells having a chimera-forming capacity that are selected from a heterogeneous cell population.
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Inventors:
ENDO HITOSHI (JP)
NAGAO YASUMITSU (JP)
HANAZONO YUTAKA (JP)
TOMINAGA KAORU (JP)
OHMORI TSUKASA (JP)
NAGAO YASUMITSU (JP)
HANAZONO YUTAKA (JP)
TOMINAGA KAORU (JP)
OHMORI TSUKASA (JP)
Application Number:
PCT/JP2015/078699
Publication Date:
April 07, 2016
Filing Date:
October 02, 2015
Export Citation:
Assignee:
UNIV JICHI MEDICAL (JP)
International Classes:
C12N5/0735; C12N5/10; C12Q1/02; A01K67/027; C12N15/09; C12Q1/68
Domestic Patent References:
| WO2014119627A1 | 2014-08-07 | |||
| WO2006009297A1 | 2006-01-26 | |||
| WO2012029784A1 | 2012-03-08 |
Other References:
GAFNI O. ET AL.: "Derivation of novel human ground state naive pluripotent stem cells", NATURE, vol. 504, no. 7479, pages 282 - 286, XP055128176, DOI: doi:10.1038/nature12745
HANNA J. ET AL.: "Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs", PROC. NATL. ACAD. SCI., vol. 107, no. 20, 18 May 2010 (2010-05-18), pages 9222 - 9227, XP055054545, DOI: doi:10.1073/pnas.1004584107
FUJISHIRO S.H. ET AL.: "Generation of naive- like porcine-induced pluripotent stem cells capable of contributing to embryonic and fetal development", STEM CELLS DEV., vol. 22, no. 3, 1 February 2013 (2013-02-01), pages 473 - 482
HANNA J. ET AL.: "Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs", PROC. NATL. ACAD. SCI., vol. 107, no. 20, 18 May 2010 (2010-05-18), pages 9222 - 9227, XP055054545, DOI: doi:10.1073/pnas.1004584107
FUJISHIRO S.H. ET AL.: "Generation of naive- like porcine-induced pluripotent stem cells capable of contributing to embryonic and fetal development", STEM CELLS DEV., vol. 22, no. 3, 1 February 2013 (2013-02-01), pages 473 - 482
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)
Ono Shinjiro (JP)
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