Title:
METHOD OF SCREENING GENE AFFECTING PATHOLOGICAL CONDITIONS OR SURVIVAL OF ANIMAL INFECTED WITH PATHOGEN
Document Type and Number:
WIPO Patent Application WO/2002/038753
Kind Code:
A1
Abstract:
By using a full-length cDNA library as a substitute for a genomic DNA library employed in the conventional ELI method as DNA for immunization of animals, it becomes possible to efficiently screen a gene which affects the pathological conditions or survival of an animal infected with a pathogen.
Inventors:
WATANABE JUNICHI (JP)
Application Number:
PCT/JP2001/008371
Publication Date:
May 16, 2002
Filing Date:
September 26, 2001
Export Citation:
Assignee:
WATANABE JUNICHI (JP)
International Classes:
A61P33/06; C12N15/10; C12Q1/68; (IPC1-7): C12N15/09; A61K31/711; A61K48/00; A61P33/06; C12Q1/68; G01N33/15; G01N33/50
Domestic Patent References:
| WO1995026196A1 | 1995-10-05 | |||
| WO1996012808A1 | 1996-05-02 |
Foreign References:
| JP2000189178A | 2000-07-11 | |||
| JPH1118771A | 1999-01-26 | |||
| JPH09263599A | 1997-10-07 |
Other References:
Junichi WATANABE et al., "FULL-malaria: a database for a full-length enriched cDNA library from human malaria parasite, Plasmodium falciparum", Nucleic Acids Research, January, 2001, Vol. 29, No. 1, pages 70 to 71
David PIEDRAFITA et al., "Protective Immune Responses Induced by Vaccination with an Expression Genomic Library of Leishmania major", J. Immunol., 01 August, 1999, vol.163, No. 3, pages 1467 to 1472
Michael A. BARRY et al., "Protection against mycoplasma infection using expression-library immunization", Nature, 19 October, 1995, Vol. 377, No. 6550, pages 632 to 635
David PIEDRAFITA et al., "Protective Immune Responses Induced by Vaccination with an Expression Genomic Library of Leishmania major", J. Immunol., 01 August, 1999, vol.163, No. 3, pages 1467 to 1472
Michael A. BARRY et al., "Protection against mycoplasma infection using expression-library immunization", Nature, 19 October, 1995, Vol. 377, No. 6550, pages 632 to 635
Attorney, Agent or Firm:
Shimizu, Hatsushi (Oroshi-machi Tsuchiura-shi, Ibaraki, JP)
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