Title:
METHOD OF SEPARATING NUCLEIC ACID, MICROREACTOR FOR TESTING NUCLEIC ACID AND NUCLEIC ACID TEST SYSTEM
Document Type and Number:
WIPO Patent Application WO/2007/055165
Kind Code:
A1
Abstract:
It is intended to provide a microreactor for testing a nucleic acid and a nucleic acid
test system which have a pretreatment means and enable the performance of a highly
reliable test. A nucleic acid test system comprising a chip component for each
specimen which has elements for supplying reagents and liquids and a control/detection
component which is the main body of the test apparatus and provided separately
from the chip component. Since this system has a specimen-pretreatment part
for conducting a pretreatment by extracting a nucleic acid from the specimen and
concentrating the same, the target substance can be concentrated even in the
case of using a dilute sample while simultaneously removing a harmful substance interfering
the reaction and contaminants causing clogging in a channel. Moreover, this
system has such a channel constitution as allowing the simultaneous analysis of
a positive control and a negative control. Owing to this constitution, it scarcely suffers
from serious problems in microanalysis or amplification, for example, cross
contamination and carry-over contamination.
Inventors:
NAKAJIMA AKIHISA (JP)
MIYAZAKI KOJI (JP)
SANDO YASUHIRO (JP)
HIGASHINO KUSUNOKI (JP)
AOKI YOUICHI (JP)
MIYAZAKI KOJI (JP)
SANDO YASUHIRO (JP)
HIGASHINO KUSUNOKI (JP)
AOKI YOUICHI (JP)
Application Number:
PCT/JP2006/322086
Publication Date:
May 18, 2007
Filing Date:
November 06, 2006
Export Citation:
Assignee:
KONICA MINOLTA MED & GRAPHIC (JP)
NAKAJIMA AKIHISA (JP)
MIYAZAKI KOJI (JP)
SANDO YASUHIRO (JP)
HIGASHINO KUSUNOKI (JP)
AOKI YOUICHI (JP)
NAKAJIMA AKIHISA (JP)
MIYAZAKI KOJI (JP)
SANDO YASUHIRO (JP)
HIGASHINO KUSUNOKI (JP)
AOKI YOUICHI (JP)
International Classes:
C12N15/09; C12M1/00; C12M1/34; C12M3/06; G01N35/08; G01N37/00
Domestic Patent References:
| WO2002023180A1 | 2002-03-21 |
Foreign References:
| JP2003202347A | 2003-07-18 | |||
| JP2003522521A | 2003-07-29 | |||
| JP2004329034A | 2004-11-25 | |||
| JP2006121935A | 2006-05-18 | |||
| JP2004000217A | 2004-01-08 | |||
| JP2004108285A | 2004-04-08 |
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