Title:
METHOD FOR THERAPEUTIC USE
Document Type and Number:
WIPO Patent Application WO/2010/106127
Kind Code:
A3
Abstract:
The present invention is related to methods for the therapeutic use in the treatment of diseases and disorders where T-helper independent antibody responses are beneficial. In particular, the present invention relates to a method wherein these diseases and disorders above are treated in immunocompromised or autoimmune diseased animals or humans. Even more particular the present invention relates to the treatment of Alzheimer's disease in immunocompromised or autoimmune diseased animals or humans or where inflammatory reactions need to be specifically avoided.
Inventors:
PFEIFER ANDREA (CH)
MUHS ANDREAS (CH)
PIHLGREN MARIA (CH)
MUHS ANDREAS (CH)
PIHLGREN MARIA (CH)
Application Number:
PCT/EP2010/053519
Publication Date:
March 31, 2011
Filing Date:
March 18, 2010
Export Citation:
Assignee:
AC IMMUNE SA (CH)
PFEIFER ANDREA (CH)
MUHS ANDREAS (CH)
PIHLGREN MARIA (CH)
PFEIFER ANDREA (CH)
MUHS ANDREAS (CH)
PIHLGREN MARIA (CH)
International Classes:
A61K39/00; C07K14/47; A61P25/28
Domestic Patent References:
| WO2010115843A2 | 2010-10-14 | |||
| WO2007068411A2 | 2007-06-21 | |||
| WO2005081872A2 | 2005-09-09 |
Foreign References:
| US20080050383A1 | 2008-02-28 | |||
| US20060073158A1 | 2006-04-06 |
Other References:
MUHS ANDREAS ET AL: "Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES (PNAS), NATIONAL ACADEMY OF SCIENCE, US LNKD- DOI:10.1073/PNAS.0703137104, vol. 104, no. 23, 5 June 2007 (2007-06-05), pages 9810 - 9815, XP002542049, ISSN: 0027-8424
DOMINGUEZ D I ET AL: "Novel therapeutic strategies provide the real test for the amyloid hypothesis of Alzheimer's disease", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER, HAYWARTH, GB LNKD- DOI:10.1016/S0165-6147(02)02038-2, vol. 23, no. 7, 1 July 2002 (2002-07-01), pages 324 - 330, XP004370517, ISSN: 0165-6147
SELA M ET AL: "THERAPEUTIC VACCINES: REALITIES OF TODAY AND HOPES FOR THE FUTURE", DRUG DISCOVERY TODAY, ELSEVIER, RAHWAY, NJ, US LNKD- DOI:10.1016/S1359-6446(02)02296-1, vol. 7, no. 12, 15 June 2002 (2002-06-15), pages 664 - 673, XP001205932, ISSN: 1359-6446
TABIRA TAKESHI: "Immunization Therapy for Alzheimer Disease: A Comprehensive Review of Active Immunization Strategies", TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, vol. 220, no. 2, February 2010 (2010-02-01), pages 95 - 106, XP002599098, ISSN: 0040-8727
DOMINGUEZ D I ET AL: "Novel therapeutic strategies provide the real test for the amyloid hypothesis of Alzheimer's disease", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER, HAYWARTH, GB LNKD- DOI:10.1016/S0165-6147(02)02038-2, vol. 23, no. 7, 1 July 2002 (2002-07-01), pages 324 - 330, XP004370517, ISSN: 0165-6147
SELA M ET AL: "THERAPEUTIC VACCINES: REALITIES OF TODAY AND HOPES FOR THE FUTURE", DRUG DISCOVERY TODAY, ELSEVIER, RAHWAY, NJ, US LNKD- DOI:10.1016/S1359-6446(02)02296-1, vol. 7, no. 12, 15 June 2002 (2002-06-15), pages 664 - 673, XP001205932, ISSN: 1359-6446
TABIRA TAKESHI: "Immunization Therapy for Alzheimer Disease: A Comprehensive Review of Active Immunization Strategies", TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, vol. 220, no. 2, February 2010 (2010-02-01), pages 95 - 106, XP002599098, ISSN: 0040-8727
Attorney, Agent or Firm:
VOSSIUS & PARTNER (München, München, DE)
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