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Title:
METHODS AND COMPOSITIONS FOR TREATING MALIGNANCIES WITH DENDRITIC CELLS
Document Type and Number:
WIPO Patent Application WO/2015/179469
Kind Code:
A3
Abstract:
This invention provides methods and compositions for the treatment and/or prevention of cancer, including solid malignancies and hematologic malignancies. In particular, the present invention relates to immunotherapy using antigen-presenting cells loaded with tumor associated peptide antigens (TAPAs). If a subject expresses at least one tumor-associated antigen, the subject can be treated by antigen-presenting cells (e.g., dendritic cells) loaded with at least one tumor-associated peptide antigen derived from the tumor-associated antigen (s) expressed by the subject. This personalized immunotherapy induces or enhances immune responses to cells that express tumor-associated antigen(s).

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Inventors:
CHIRIVA-INTERNATI MAURIZIO (US)
Application Number:
PCT/US2015/031681
Publication Date:
April 07, 2016
Filing Date:
May 20, 2015
Export Citation:
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Assignee:
KIROMIC LLC (US)
International Classes:
A61K35/12; C12N5/0783; C12N5/0784
Foreign References:
US20090017000A12009-01-15
US20090075832A12009-03-19
US6479286B12002-11-12
US20140107391A12014-04-17
US20050197314A12005-09-08
US20100284976A12010-11-11
Other References:
See also references of EP 3145516A4
Attorney, Agent or Firm:
DAVITZ, Michael, A. et al. (333 W. San Carlos St. Suite 20, San Jose CA, US)
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