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Title:
METHODS OF DETECTING CANCER USING CELLULAR AUTOFLUORESCENCE
Document Type and Number:
WIPO Patent Application WO2001069199
Kind Code:
A3
Abstract:
Methods useful in detecting abnormal cells and tissues based upon measurement of tryptophan-associated autofluorescence are disclosed. The methods involve exposing cells to ultraviolet light; measuring autofluorescence at a wavelength indicative of tryptophan emission; and determining that the cells constitute abnormal tissue of emission intensity exceeds that of normal cells. The methods can detect and distinguish abnormal cell development in metaplasia, hyperplasia, dysplasia and cancer. The method also detects the presence of inflammation.

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Inventors:
BANERJEE BHASKAR (US)
Application Number:
PCT/US2001/007589
Publication Date:
March 28, 2002
Filing Date:
March 09, 2001
Export Citation:
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Assignee:
BANERJEE BHASKAR (US)
International Classes:
G01N21/64; A61B1/00; A61B5/00; A61K49/00; C12Q1/02; G01N33/48; G01N33/483; G01N33/50; G01N33/533; (IPC1-7): A61B6/00
Foreign References:
US5769081A1998-06-23
US5419323A1995-05-30
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