Title:
METHODS FOR DISEASE SCREENING
Document Type and Number:
WIPO Patent Application WO2004113574
Kind Code:
A3
Abstract:
Methods of the invention generally include measuring a quantitative amount of nucleic acid in a patient sample, and optionally, performing additional disease testing on the patient. Methods of the invention are useful in screening disease in a patient, such as cancer.
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Inventors:
SHUBER ANTHONY P (US)
Application Number:
PCT/US2004/019732
Publication Date:
April 14, 2005
Filing Date:
June 21, 2004
Export Citation:
Assignee:
EXACT SCIENCES CORP (US)
SHUBER ANTHONY P (US)
SHUBER ANTHONY P (US)
International Classes:
C12Q1/68; (IPC1-7): C12Q1/68
Domestic Patent References:
| WO2001042502A2 | 2001-06-14 | |||
| WO2002092858A2 | 2002-11-21 | |||
| WO2004079004A1 | 2004-09-16 |
Other References:
LOKTIONOV A ET AL: "Quantitation of DNA from exfoliated colonocytes isolated from human stool surface as a novel noninvasive screening test for colorectal cancer.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. FEB 1998, vol. 4, no. 2, February 1998 (1998-02-01), pages 337 - 342, XP008040461, ISSN: 1078-0432
AHLQUIST D A ET AL: "COLORECTAL CANCER SCREENING BY DETECTION OF ALTERED HUMAN DNA IN STOOL: FEASIBILITY OF A MULTITARGET ASSAY PANEL", GASTROENTEROLOGY, W.B.SAUNDERS COMPANY, PHILADELPHIA, US, vol. 119, no. 5, November 2000 (2000-11-01), pages 1219 - 1227, XP001118414, ISSN: 0016-5085
VILLA E ET AL: "Identification of subjects at risk for colorectal carcinoma through a test based on K-ras determination in the stool.", GASTROENTEROLOGY. MAY 1996, vol. 110, no. 5, May 1996 (1996-05-01), pages 1346 - 1353, XP008040495, ISSN: 0016-5085
KLAASSEN CORNÉ H W ET AL: "Quantification of human DNA in feces as a diagnostic test for the presence of colorectal cancer.", CLINICAL CHEMISTRY. JUL 2003, vol. 49, no. 7, July 2003 (2003-07-01), pages 1185 - 1187, XP002310510, ISSN: 0009-9147
AHLQUIST D A ET AL: "COLORECTAL CANCER SCREENING BY DETECTION OF ALTERED HUMAN DNA IN STOOL: FEASIBILITY OF A MULTITARGET ASSAY PANEL", GASTROENTEROLOGY, W.B.SAUNDERS COMPANY, PHILADELPHIA, US, vol. 119, no. 5, November 2000 (2000-11-01), pages 1219 - 1227, XP001118414, ISSN: 0016-5085
VILLA E ET AL: "Identification of subjects at risk for colorectal carcinoma through a test based on K-ras determination in the stool.", GASTROENTEROLOGY. MAY 1996, vol. 110, no. 5, May 1996 (1996-05-01), pages 1346 - 1353, XP008040495, ISSN: 0016-5085
KLAASSEN CORNÉ H W ET AL: "Quantification of human DNA in feces as a diagnostic test for the presence of colorectal cancer.", CLINICAL CHEMISTRY. JUL 2003, vol. 49, no. 7, July 2003 (2003-07-01), pages 1185 - 1187, XP002310510, ISSN: 0009-9147
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