Title:
METHODS FOR ENHANCING THE POTENCY OF HCV NEUTRALIZING ANTIBODIES
Document Type and Number:
WIPO Patent Application WO2006103493
Kind Code:
A8
Abstract:
The present invention relates to a method for selecting an HCV epitope which is not sensitive to HDL-mediated decrease of the neutralizing capacity of anti-HCV antibodies, as well as to methods for treating an HCV-infected patient or a subject who has been exposed to HCV, comprising administering to the patient a therapeutically effective amount of a compound inhibiting HCV/HDL/SR-BI interplay, or comprising reducing the plasma loads of HDL.
Inventors:
COSSET FRANCOIS-LOIC (FR)
BARTOSCH BIRKE (FR)
LAVILLETTE DIMITRI (FR)
DREUX MARLENE (FR)
KLATZMANN DAVID (FR)
DALBA CHARLOTTE (FR)
BARTOSCH BIRKE (FR)
LAVILLETTE DIMITRI (FR)
DREUX MARLENE (FR)
KLATZMANN DAVID (FR)
DALBA CHARLOTTE (FR)
Application Number:
PCT/IB2005/004012
Publication Date:
November 16, 2006
Filing Date:
December 21, 2005
Export Citation:
Assignee:
EPIXIS (FR)
INST NAT SANTE RECH MED (FR)
ECOLE NORM SUPERIEURE LYON (FR)
UNIV PARIS CURIE (FR)
COSSET FRANCOIS-LOIC (FR)
BARTOSCH BIRKE (FR)
LAVILLETTE DIMITRI (FR)
DREUX MARLENE (FR)
KLATZMANN DAVID (FR)
DALBA CHARLOTTE (FR)
INST NAT SANTE RECH MED (FR)
ECOLE NORM SUPERIEURE LYON (FR)
UNIV PARIS CURIE (FR)
COSSET FRANCOIS-LOIC (FR)
BARTOSCH BIRKE (FR)
LAVILLETTE DIMITRI (FR)
DREUX MARLENE (FR)
KLATZMANN DAVID (FR)
DALBA CHARLOTTE (FR)
International Classes:
G01N33/576
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