METHODS OF INHIBITING AND TREATING BACTERIAL BIOFILMS BY METAL CHELATORS

Title:

METHODS OF INHIBITING AND TREATING BACTERIAL BIOFILMS BY METAL CHELATORS

Document Type and Number:

WIPO Patent Application WO2003088914

Kind Code:

A3

Abstract:

The invention presented herein provides methods and compositions for the prevention and treatment of bacterial infections. The methods are based on the discovery that depletion of bioavailable iron stimulates surface motility in bacteria thus inhibiting the ability of a bacterial population to develop into a biofilm.

More Like This:

JP2003523205	Description: A nematode 5HT3 receptor, a polynucleotide molecule encoding it, and an antagonist thereof.
JP2023134343	METHOD FOR CULTIVATING CITRUS PLANT AND LIQUID COMPOSITION
JP3420129	ANTIMICROBIAL AGENT COMPRISING SHELL, CLEANING OF WATER USING THE ANTIMICROBIAL AGENT AND WASHING OF FIELD CROP USING THE ANTIMICROBIAL AGENT

Inventors:

SINGH PRADEEP K (US)
WELSH MICHAEL J (US)
GREENBERG E PETER (US)

Application Number:

PCT/US2003/012128

Publication Date:

February 26, 2004

Filing Date:

April 18, 2003

Export Citation:

Click for automatic bibliography generation Help

Assignee:

UNIV IOWA RES FOUND (US)
SINGH PRADEEP K (US)
WELSH MICHAEL J (US)
GREENBERG E PETER (US)

International Classes:

A01N61/00; A01N63/50; A23B4/20; A23B4/22; A23L3/3463; A23L3/3526; A23L3/3571; A61L2/00; A61L2/16; A61L2/18; (IPC1-7): A61K38/40; A61K9/00; C07K14/00

Domestic Patent References:

WO1998006425A1

1998-02-19

Foreign References:

US5198419A	1993-03-30
EP0568200A2	1993-11-03
US20020123077A1	2002-09-05

Other References:

DARBY ET AL.: "Innate defense evicts bacterial squatters", NATURE IMMUNOLOGY, vol. 3, no. 7, July 2002 (2002-07-01), pages 602 - 604, XP002971539

Download PDF:

View/Download PDF PDF Help

Previous Patent: PEPTIDE DEFORMYLASE ACTIVATED PRODRUGS

Next Patent: NOVEL SODIUM CHANNEL BLOCKERS