Title:
METHODS AND MATERIALS FOR TREATING CANCER
Document Type and Number:
WIPO Patent Application WO/2023/081803
Kind Code:
A3
Abstract:
This document relates to methods and materials involved in treating cancer. For example, methods and materials for using (a) APCs (e.g., dendritic cells) designed to release a viral vector that can infect a T cell (e.g., an infectious retroviral vector or an infectious lentiviral vector) and drive expression of an antigen receptor (e.g., a CAR) within that T cell and (b) an antigenic composition containing one or more antigens that can be presented to T cells within the mammal by APCs of the administered population and/or by other APCs within the mammal to produce dual specific CAR+ memory T cells are provided.
Inventors:
VILE RICHARD G (US)
DIAZ MARCANO ROSA M (US)
KOTTKE TIMOTHY J (US)
TONNE JASON M (US)
DIAZ MARCANO ROSA M (US)
KOTTKE TIMOTHY J (US)
TONNE JASON M (US)
Application Number:
PCT/US2022/079279
Publication Date:
August 17, 2023
Filing Date:
November 04, 2022
Export Citation:
Assignee:
MAYO FOUND MEDICAL EDUCATION & RES (US)
International Classes:
C12N5/0784; A61K35/15; A61K35/17; A61K39/00; A61P35/00; C12N15/86; C12N15/867
Foreign References:
| US20160199412A1 | 2016-07-14 | |||
| US20180334651A1 | 2018-11-22 | |||
| US20190284548A1 | 2019-09-19 |
Attorney, Agent or Firm:
WILLIS, Margaret S. et al. (US)
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