METHODS OF SCREENING FOR RISK OF PROLIFERATIVE DISEASE AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASE

Title:

METHODS OF SCREENING FOR RISK OF PROLIFERATIVE DISEASE AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASE

Document Type and Number:

WIPO Patent Application WO2000023624

Kind Code:

A9

Abstract:

A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore.

More Like This:

WO/2018/227202	DETERMINATION OF CANCER TYPE IN A SUBJECT BY PROBABILISTIC MODELING OF CIRCULATING NUCLEIC ACID FRAGMENT ENDPOINTS
JP2017524943	Prediction of S. aureus disease
JP5952994	A crop science elite soybean which has a high beta Conglycinin content

Inventors:

BOUSTANY ROSE-MARY N (US)
GUO WEI-XING (US)
AMALFITANO ANDREA (US)

Application Number:

PCT/US1999/024695

Publication Date:

September 21, 2000

Filing Date:

October 21, 1999

Export Citation:

Click for automatic bibliography generation Help

Assignee:

UNIV DUKE (US)
BOUSTANY ROSE MARY N (US)
GUO WEI XING (US)
AMALFITANO ANDREA (US)

International Classes:

C12Q1/68; C12Q1/6883; G01N33/50; G01N33/574; (IPC1-7): C12Q1/68

Download PDF:

View/Download PDF PDF Help

Previous Patent: POLYMORPHISM IN Fas PROMOTER AND Fas LIGAND PROMOTER

Next Patent: ISOLATED NUCLEIC ACID MOLECULES WHICH ENCODE SCP PROTEINS, AND USES THEREOF