Title:
MICRONEEDLE DEVICE
Document Type and Number:
WIPO Patent Application WO/2018/123982
Kind Code:
A1
Abstract:
The microneedle device according to the present invention comprises: a substrate, a microneedle disposed on the substrate, and a coating formed on the microneedle, the coating containing dexmedetomidine or a pharmaceutically acceptable salt thereof, and isoproterenol or a pharmaceutically acceptable salt thereof. Using said microneedle device results in a rapid increase in plasma dexmedetomidine concentration following application of the microneedle device.
Inventors:
HORI RYOTA (JP)
KOGURE TOSHIHIRO (JP)
TOKUMOTO SEIJI (JP)
NISHIMURA SHINPEI (JP)
KOGURE TOSHIHIRO (JP)
TOKUMOTO SEIJI (JP)
NISHIMURA SHINPEI (JP)
Application Number:
PCT/JP2017/046456
Publication Date:
July 05, 2018
Filing Date:
December 25, 2017
Export Citation:
Assignee:
HISAMITSU PHARMACEUTICAL CO (JP)
International Classes:
A61K31/4174; A61L31/08; A61M37/00; A61P25/20
Domestic Patent References:
| WO2016039418A1 | 2016-03-17 | |||
| WO2010063030A2 | 2010-06-03 |
Foreign References:
| JP2014507473A | 2014-03-27 | |||
| JP2016532642A | 2016-10-20 | |||
| JP2014508746A | 2014-04-10 | |||
| JPH05503916A | 1993-06-24 | |||
| JP2001506904A | 2001-05-29 | |||
| JP2001506904A | 2001-05-29 |
Other References:
See also references of EP 3560495A4
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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