Title:
MICROPARTICLE PHARMACEUTICAL COMPOSITIONS FOR INTRATUMORAL DELIVERY
Document Type and Number:
WIPO Patent Application WO2003090722
Kind Code:
A3
Abstract:
Provided are microparticles including paclitaxel, methods for making them, and pharmaceutical compositions containing them. Also provided are methods of treating tumors including the step of intratumorally injecting the paclitaxel-containing microspheres of the present invention.
Inventors:
LERNER E ITZHAK (IL)
FLASHNER-BARAK MOSHE (IL)
TZAFRIRI ABRAHAM (IL)
PARNESS HANNA (IL)
SMITH ALAN (GB)
HINCHCLIFFE MICHAEL (GB)
FLASHNER-BARAK MOSHE (IL)
TZAFRIRI ABRAHAM (IL)
PARNESS HANNA (IL)
SMITH ALAN (GB)
HINCHCLIFFE MICHAEL (GB)
Application Number:
PCT/US2003/013018
Publication Date:
January 15, 2004
Filing Date:
April 24, 2003
Export Citation:
Assignee:
TEVA PHARMA (US)
WEST PHARM SERV DRUG RES LTD (GB)
TEVA PHARMA (US)
WEST PHARM SERV INC (US)
LERNER E ITZHAK (IL)
FLASHNER-BARAK MOSHE (IL)
TZAFRIRI ABRAHAM (IL)
PARNESS HANNA (IL)
SMITH ALAN (GB)
HINCHCLIFFE MICHAEL (GB)
WEST PHARM SERV DRUG RES LTD (GB)
TEVA PHARMA (US)
WEST PHARM SERV INC (US)
LERNER E ITZHAK (IL)
FLASHNER-BARAK MOSHE (IL)
TZAFRIRI ABRAHAM (IL)
PARNESS HANNA (IL)
SMITH ALAN (GB)
HINCHCLIFFE MICHAEL (GB)
International Classes:
A61K9/00; A61K9/16; A61K9/14; A61K31/337; A61K47/30; A61K47/32; A61K47/36; A61K47/38; A61P35/00; (IPC1-7): A61K9/16; A61K31/337
Foreign References:
| US20020041896A1 | 2002-04-11 |
Other References:
DAYANAND, SHARMA; ET AL.: "Novel Taxol Formulation: Polyvinylpyrrolidone Nanoparticle-Encapsulated Taxol for Drug Delivery in Cancer Therapy", ONCOLOGY RESEARCH, vol. 8, no. 7/8, 1996, US, pages 281 - 286, XP001036566
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