Title:
MODULATING UREA DEGRADATION IN WINE YEAST
Document Type and Number:
WIPO Patent Application WO2003040379
Kind Code:
A3
Abstract:
The invention provides yeast strains transformed to reduce nitrogen catabolite repression of a gene encoding a urea degrading enzymatic activity expressed by the yeast strain under fermenting conditions. Strains ofSaccharomyces cerevisiae are for example provided having enhanced DUR1,2 urea carboxylase-allophanate hydrolase activity under wine fermenting conditions.
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Inventors:
VAN VUUREN HENDRIK JURGENS JAN (CA)
LONVAUD ALINE (FR)
COULON JOANA (BE)
INGLIS DEBRA (CA)
LONVAUD ALINE (FR)
COULON JOANA (BE)
INGLIS DEBRA (CA)
Application Number:
PCT/CA2002/001719
Publication Date:
September 04, 2003
Filing Date:
November 06, 2002
Export Citation:
Assignee:
UNIV BRITISH COLUMBIA (CA)
VAN VUUREN HENDRIK JURGENS JAN (CA)
LONVAUD ALINE (FR)
COULON JOANA (BE)
INGLIS DEBRA (CA)
VAN VUUREN HENDRIK JURGENS JAN (CA)
LONVAUD ALINE (FR)
COULON JOANA (BE)
INGLIS DEBRA (CA)
International Classes:
C12C12/00; C12G1/022; C12N1/19; C12G1/00; C12N9/00; C12N9/80; C12N15/09; C12N15/81; C12P7/06; C12R1/865; (IPC1-7): C12R1/865; C12N15/81; C12N9/80
Foreign References:
| JPH05244959A | 1993-09-24 |
Other References:
VAN RENSBURG P ET AL: "Enzymes in winemaking: Harnessing natural catalysts for efficient biotransformations: A review.", SOUTH AFRICAN JOURNAL OF ENOLOGY AND VITICULTURE, vol. 21, no. Special Issue, 2000, pages 52 - 73, XP001152509, ISSN: 0253-939X
ALBERT M ET AL: "Effect of Diammonium phosphate additions on the production of ethyl carbamate during wine fermentations.", AMERICAN JOURNAL OF ENOLOGY AND VITICULTURE, vol. 51, no. 3, 2000, 50th Annual Meeting of the American Society for Enology and Viticulture;Seattle, Washington, USA; June, 2000, pages 300, XP009010708, ISSN: 0002-9254
DATABASE GENESEQ [online] 10 May 1994 (1994-05-10), "Urea amidolyase gene", XP002240762, Database accession no. AAQ49460
GARY PIGEAU: "Characterization of wild-type and mutant ureases of the fission yeast Schizosaccharomyces pombe", BROCK UNIVERSITY, 2000, XP002240760, Retrieved from the Internet [retrieved on 20030512]
VISSER ET AL.: "Engineering an acid urease for heterologous expression in Saccharomyces cerevisiae", CURRENT GENETICS, vol. 35, no. 3/4, 1999, pages 321, XP009010903
GENBAUFFE F S ET AL: "INDUCTION AND REPRESSION OF THE UREA AMIDOLYASE GENE IN SACCHAROMYCES-CEREVISIAE", MOLECULAR AND CELLULAR BIOLOGY, vol. 6, no. 11, 1986, pages 3954 - 3964, XP009010650, ISSN: 0270-7306
SUMRADA R A ET AL: "UREA CARBOXYLASE AND ALLOPHANATE HYDROLASE ARE COMPONENTS OF A MULTI FUNCTIONAL PROTEIN IN YEAST", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 257, no. 15, 1982, pages 9119 - 9127, XP002240761, ISSN: 0021-9258
ALBERT M ET AL: "Effect of Diammonium phosphate additions on the production of ethyl carbamate during wine fermentations.", AMERICAN JOURNAL OF ENOLOGY AND VITICULTURE, vol. 51, no. 3, 2000, 50th Annual Meeting of the American Society for Enology and Viticulture;Seattle, Washington, USA; June, 2000, pages 300, XP009010708, ISSN: 0002-9254
DATABASE GENESEQ [online] 10 May 1994 (1994-05-10), "Urea amidolyase gene", XP002240762, Database accession no. AAQ49460
GARY PIGEAU: "Characterization of wild-type and mutant ureases of the fission yeast Schizosaccharomyces pombe", BROCK UNIVERSITY, 2000, XP002240760, Retrieved from the Internet
VISSER ET AL.: "Engineering an acid urease for heterologous expression in Saccharomyces cerevisiae", CURRENT GENETICS, vol. 35, no. 3/4, 1999, pages 321, XP009010903
GENBAUFFE F S ET AL: "INDUCTION AND REPRESSION OF THE UREA AMIDOLYASE GENE IN SACCHAROMYCES-CEREVISIAE", MOLECULAR AND CELLULAR BIOLOGY, vol. 6, no. 11, 1986, pages 3954 - 3964, XP009010650, ISSN: 0270-7306
SUMRADA R A ET AL: "UREA CARBOXYLASE AND ALLOPHANATE HYDROLASE ARE COMPONENTS OF A MULTI FUNCTIONAL PROTEIN IN YEAST", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 257, no. 15, 1982, pages 9119 - 9127, XP002240761, ISSN: 0021-9258
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