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Title:
MOLECULES FOR DISEASE DETECTION AND TREATMENT
Document Type and Number:
WIPO Patent Application WO2003062379
Kind Code:
A3
Abstract:
The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce antibodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.

Inventors:
JONES ANISSA L (US)
DAHL CHRISTOPHER R (US)
GIETZEN DARRYL (US)
CHINN JOYCE (US)
DUFOUR GERARD E (US)
JACKSON JENNIFER L (US)
YU JIMMY Y (US)
TUASON OLIVIA (US)
YAP PIERRE E (US)
AMSHEY STEFAN R (US)
DAM TAM C (US)
LIU TOMMY F (US)
GERSTIN EDWARD H JR (US)
PERALTA CAREYNA H (US)
LEWIS SAMANTHA A (US)
CHEN ALICE J (US)
MARWAHA RAKESH (US)
LAN RUTH Y (US)
URASHKA MICHAEL E (US)
KRISTNAM SREENIVASA R (US)
KOLLURU VIJAYKUMAR (US)
PANESAR IQBAL S (US)
Application Number:
PCT/US2003/001363
Publication Date:
February 19, 2004
Filing Date:
January 14, 2003
Export Citation:
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Assignee:
INCYTE GENOMICS INC (US)
JONES ANISSA L (US)
DAHL CHRISTOPHER R (US)
GIETZEN DARRYL (US)
CHINN JOYCE (US)
DUFOUR GERARD E (US)
JACKSON JENNIFER L (US)
YU JIMMY Y (US)
TUASON OLIVIA (US)
YAP PIERRE E (US)
AMSHEY STEFAN R (US)
DAM TAM C (US)
LIU TOMMY F (US)
GERSTIN EDWARD H JR (US)
PERALTA CAREYNA H (US)
LEWIS SAMANTHA A (US)
CHEN ALICE J (US)
MARWAHA RAKESH (US)
LAN RUTH Y (US)
URASHKA MICHAEL E (US)
KRISTNAM SREENIVASA R (US)
KOLLURU VIJAYKUMAR (US)
PANESAR IQBAL S (US)
International Classes:
C12N15/12; C12Q1/68; (IPC1-7): C12N15/11; C07K14/00; C07K14/435; C12N15/00; C12N15/12; C12Q1/68
Domestic Patent References:
WO2001053312A12001-07-26
Foreign References:
EP1033401A22000-09-06
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