Title:
MULTI-FUNCTIONAL TWO-PHOTON MICROSCOPIC IMAGING SYSTEM
Document Type and Number:
WIPO Patent Application WO/2023/015798
Kind Code:
A1
Abstract:
A multi-functional two-photon microscopic imaging system. A first excitation light source (1), a first photoelectric modulator (2), a first beam expanding apparatus (3), a reflecting mirror (4) and a first scanning apparatus (5) constitute a light stimulation module; a second excitation light source (19), a second photoelectric modulator (20), a second beam expanding apparatus (21) and a second scanning apparatus (22) constitute a point scanning imaging module; and a third excitation light source (23), a third photoelectric modulator (24), a third beam expanding apparatus (25) and a third scanning apparatus (26) constitute a line scanning imaging module. The system effectively integrates the techniques of point scanning and line scanning, and can realize the fusion and synchronization of three functions: structural imaging of living biological tissue, optogenetics regulation and control of cells, and imaging of physiological activities (e.g. a neuronal calcium signal).
Inventors:
LI BAOQIANG (CN)
BI GUOQIANG (CN)
WANG YANG (CN)
BI GUOQIANG (CN)
WANG YANG (CN)
Application Number:
PCT/CN2021/138046
Publication Date:
February 16, 2023
Filing Date:
December 14, 2021
Export Citation:
Assignee:
SHENZHEN INST ADV TECH (CN)
International Classes:
A61B5/00; G02B21/00
Domestic Patent References:
| WO2021097482A1 | 2021-05-20 |
Foreign References:
| US9234846B2 | 2016-01-12 | |||
| US20060012869A1 | 2006-01-19 | |||
| US20180321154A1 | 2018-11-08 | |||
| CN102985866A | 2013-03-20 | |||
| US20210161385A1 | 2021-06-03 | |||
| CN102551661A | 2012-07-11 |
Attorney, Agent or Firm:
BEIJING ZHONG XUN TONG DA INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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