Title:
MULTI-WELL ROTARY SYNTHESIZER WITH SEALING WASTE TUBE SYSTEM
Document Type and Number:
WIPO Patent Application WO2002028524
Kind Code:
A9
Abstract:
An apparatus (100) for synthesizing polymer chains includes a controller (480), a plurality of precision fit vials (181) circularly arranged in multiple banks (115, 125) on a cartridge (170, 300), a drain (740) corresponding to each bank of vials (115, 125), a chamberbowl (400), a plurality of valves for delivering reagents to selective vials (181), and a waste tube system (430) for purging material from the vials (181). A purging operation can be selectively performed on one or more of the banks of vials (115, 125). The multiple banks of valves (110, 120, 130, 470) provide an additional number of reagent choices while operating in a serial mode and faster reagent distribution while operating in a parallel mode. The plurality of vials (181) are stored in the cartridge (170, 300) and are divided among individual banks (115, 125) wherein each bank of vials (115, 125) has a corresponding drain. There is at least one waste tube system (430) for expelling the reagent solution from vials (181) within a particular bank of vials (115, 125) when the waste tube system (430) is coupled to the corresponding drain. The cartridge (170, 300) holding the plurality of vials (181) rotates relative to the stationary banks of valves (110, 120, 130, 470) and the waste tube system (430).
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Inventors:
MCLUEN GARY R (US)
Application Number:
PCT/US2001/030612
Publication Date:
May 30, 2003
Filing Date:
September 27, 2001
Export Citation:
Assignee:
MCLUEN GARY R (US)
International Classes:
B01J19/00; C40B40/06; C40B40/14; C40B60/14; (IPC1-7): B01J19/00; F16K1/14; F16L37/40
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