Title:
MULTIBINDING AGENTS THAT MODULATE THE 5-HT TRANSPORTER
Document Type and Number:
WIPO Patent Application WO1999063932
Kind Code:
A9
Abstract:
Disclosed are multibinding compounds are capable of binding to a 5-HT cell membrane transporter. The multibinding compounds of this invention contain from 2 to 10 ligands covalently attached to one or more linkers. the mltibinding compounds of this invention are useful for modulating serotonin levels.
Inventors:
BEATTIE DAVID T (US)
AGGEN JAMES (US)
GRIFFIN JOHN H (US)
AGGEN JAMES (US)
GRIFFIN JOHN H (US)
Application Number:
PCT/US1999/012724
Publication Date:
March 16, 2000
Filing Date:
June 07, 1999
Export Citation:
Assignee:
ADVANCED MEDICINE INC (US)
BEATTIE DAVID T (US)
AGGEN JAMES (US)
GRIFFIN JOHN H (US)
BEATTIE DAVID T (US)
AGGEN JAMES (US)
GRIFFIN JOHN H (US)
International Classes:
A61K45/00; A61K47/48; A61P43/00; C07B61/00; C07C217/16; C07K2/00; C40B20/00; C40B40/02; C40B50/06; G01N33/15; G01N33/566; G01N33/68; G01N33/50; (IPC1-7): A61K31/58; A61K38/00; A61K39/00; A61K39/395; A61K51/00; C07D401/04; C07D401/12; C07K2/00; C07K4/00; G01N33/53; G01N33/543; G01N33/566
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