MULTIDRUG EFFLUX PUMP VARIANT, POLYNUCLEOTIDE CODING VARIANT, MICROORGANISM COMPRISING VARIANT, AND METHOD FOR PRODUCING VIOLACEIN OR DEOXYVIOLACEIN USING SAME

Title:

MULTIDRUG EFFLUX PUMP VARIANT, POLYNUCLEOTIDE CODING VARIANT, MICROORGANISM COMPRISING VARIANT, AND METHOD FOR PRODUCING VIOLACEIN OR DEOXYVIOLACEIN USING SAME

Document Type and Number:

WIPO Patent Application WO/2021/125494

Kind Code:

A1

Abstract:

The present invention relates to a multidrug efflux pump (mepA) variant, a polynucleotide that codes the variant, a microorganism comprising the variant, and a method for producing violacein or deoxyviolacein using same, the present invention being usefully applicable to the mass production of violacein or deoxyviolacein.

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Inventors:

RYU GYU RI (KR)
BAE HYUN AE (KR)
JEON AE JI (KR)
JANG JAE WOO (KR)

Application Number:

PCT/KR2020/011317

Publication Date:

June 24, 2021

Filing Date:

August 25, 2020

Export Citation:

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Assignee:

CJ CHEILJEDANG CORP (KR)

International Classes:

C07K14/31; C12N9/02; C12P17/16

Foreign References:

US20110294183A1	2011-12-01
KR20190005707A	2019-01-16
US20110183384A1	2011-07-28

Other References:

DATABASE Protein GenPept; ANONYMOUS: "MULTISPECIES: multidrug efflux MATE transporter MepA [Staphylococcus] - Protein - NCBI", XP055824455, retrieved from NCBI
SCHINDLER BRYAN D., SEO SUSAN M., BIRUKOU IVAN, BRENNAN RICHARD G., KAATZ GLENN W.: "Mutation within the mepa operator affect binding of the mepr regulatory protein and its induction by mepa substrates in staphylococcus aureus.", JOURNAL OF BACTERIOLOGY (PRINT), AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 197, no. 6, 15 March 2015 (2015-03-15), US, pages 1104 - 1114, XP055824458, ISSN: 0021-9193, DOI: 10.1128/JB.02558-14

Attorney, Agent or Firm:

Y.P.LEE, MOCK & PARTNERS (KR)

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