Title:
MULTISPECIFIC ANTIGEN BINDING PROTEINS AND METHODS OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/014855
Kind Code:
A1
Abstract:
Disclosed herein are multispecific, such as bispecific, antigen binding proteins comprising a first antigen binding domain comprising a heavy chain variable domain and a light chain variable domain, and a second antigen binding domain comprising a single-domain antibody. Pharmaceutical compositions comprising the multispecific antigen binding proteins, kits and methods of use thereof are further provided.
Inventors:
CHOU CHUAN-CHU (US)
ZHANG YAFENG (CN)
WU SHU (CN)
LIU ZHENYU (CN)
LI ZHONGDAO (CN)
ZHANG FANGLIANG (CN)
ZHANG YAFENG (CN)
WU SHU (CN)
LIU ZHENYU (CN)
LI ZHONGDAO (CN)
ZHANG FANGLIANG (CN)
Application Number:
PCT/CN2017/093644
Publication Date:
January 25, 2018
Filing Date:
July 20, 2017
Export Citation:
Assignee:
NANJING LEGEND BIOTECH CO LTD (CN)
International Classes:
C07K16/46; A61K39/395; A61P35/00; A61P37/00; C07K16/18; C07K16/24; C07K16/28; C07K16/30
Domestic Patent References:
| WO2011036460A1 | 2011-03-31 | |||
| WO2006138670A2 | 2006-12-28 |
Foreign References:
| US20140127210A1 | 2014-05-08 | |||
| CN1388136A | 2003-01-01 | |||
| CN105754990A | 2016-07-13 |
Other References:
FULKERSON, P.C. ET AL.: "Targeting eosinophils in allergy, inflammation and beyond", NATURE REVIEWS: DRUG DISCOVERY, vol. 12, 21 January 2013 (2013-01-21), pages 117 - 129, XP055559710, DOI: doi:10.1038/nrd3838
Attorney, Agent or Firm:
CHENG & PENG INTELLECTUAL PROPERTY LAW OFFICE (CN)
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