Title:
NEW GENE RECOMBINANT VACCINIA VIRUS AND UTILIZATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/107705
Kind Code:
A1
Abstract:
Provided are a vaccinia virus into which a therapeutic gene has been introduced as an exogenous gene, and a therapeutic composition containing said vaccinia virus. The vaccinia virus comprises at least one immune regulating gene as an exogenous gene.
Inventors:
NAKAMURA TAKAFUMI (JP)
KAITSURUMARU EMI (JP)
NAKATAKE MOTOMU (JP)
KUROSAKI HAJIME (JP)
KAITSURUMARU EMI (JP)
NAKATAKE MOTOMU (JP)
KUROSAKI HAJIME (JP)
Application Number:
PCT/JP2021/041825
Publication Date:
May 27, 2022
Filing Date:
November 15, 2021
Export Citation:
Assignee:
NAT UNIV CORP TOTTORI UNIV (JP)
International Classes:
C12N15/24; A61K35/768; A61K38/19; A61K38/20; C12N7/01
Domestic Patent References:
| WO2018012570A1 | 2018-01-18 | |||
| WO2020067085A1 | 2020-04-02 | |||
| WO2019143201A1 | 2019-07-25 | |||
| WO2011125469A1 | 2011-10-13 | |||
| WO2015076422A1 | 2015-05-28 | |||
| WO2005054451A1 | 2005-06-16 | |||
| WO2017014296A1 | 2017-01-26 | |||
| WO2005007824A2 | 2005-01-27 |
Foreign References:
| JP2020191128A | 2020-11-26 | |||
| US7635752B2 | 2009-12-22 | |||
| US20030031681A1 | 2003-02-13 | |||
| US6596279B1 | 2003-07-22 | |||
| US6548068B1 | 2003-04-15 | |||
| JP2019091609A | 2019-06-13 | |||
| JP2020018976W | 2020-05-12 |
Other References:
PROTEIN, NUCLEIC ACID AND ENZYME, vol. 48, no. 12, 2003, pages 1693 - 1700
HASHIZUME, CLINICAL VIROLOGY, vol. 3, no. 3, 1975, pages 269
WAGENAAR ET AL., JOURNAL OF VIROLOGY, vol. 82, no. 11, June 2008 (2008-06-01), pages 5153 - 5160
NAKAMURA ET AL., NATURE BIOTECHNOLOGY, vol. 22, no. 3, March 2004 (2004-03-01), pages 331 - 336
KRABBE ET AL., CANCERS, vol. 10, 2018, pages 216
URNOV, FYODOR D ET AL., NATURE, vol. 435, 2 June 2005 (2005-06-02), pages 642 - 651
MAHFOUZ, MAGDY M ET AL., PNAS, vol. 108, no. 6, 8 February 2011 (2011-02-08), pages 2623 - 2628
JINEK M ET AL., SCIENCE, vol. 337, 17 August 2012 (2012-08-17), pages 816 - 821
KATZ ET AL., J VIROLOGY, vol. 77, 2003, pages 12266 - 12275
MOORE ET AL., EMBO J, vol. 77, 1992, pages 1973 - 1980
KOTWAL ET AL., VIROLOGY, vol. 171, 1989, pages 579 - 58
CHILD ET AL., VIROLOGY, vol. 174, 1990, pages 625 - 629
LEE ET AL., J VIROL, vol. 66, 1992, pages 2617 - 2630
ISAACS ET AL., PROC NATL ACAD SCI USA, vol. 89, 1992, pages 628 - 632
CANCER RESEARCH, vol. 67, 2007, pages 10038 - 10046
PLOS MEDICINE, vol. 4, 2007, pages e353
PLOS PATHOGENS, vol. 6, 2010, pages e1000984
CANCER RESEARCH, vol. 65, 2005, pages 9991 - 9998
GENE THERAPY, vol. 14, 2007, pages 638 - 647
SAITO I ET AL.: "Analytical Experiment Methods for Gene Introduction and Expression", 1 September 1997, YODOSHA CO., LTD., article "Experimental Medicine: The Protocol Series"
"EMBO Journal", vol. 6, 1987, article "DNA Cloning 4: Mammal System", pages: 3379 - 3384
HAMMOND JM. ET AL., JOURNAL OF VIROLOGICAL METHODS, vol. 66, no. l, 1997, pages 135 - 138
ONCOIMMUNOLOGY, vol. 5, no. 10, 2016, pages e1220467
HASHIZUME, CLINICAL VIROLOGY, vol. 3, no. 3, 1975, pages 269
WAGENAAR ET AL., JOURNAL OF VIROLOGY, vol. 82, no. 11, June 2008 (2008-06-01), pages 5153 - 5160
NAKAMURA ET AL., NATURE BIOTECHNOLOGY, vol. 22, no. 3, March 2004 (2004-03-01), pages 331 - 336
KRABBE ET AL., CANCERS, vol. 10, 2018, pages 216
URNOV, FYODOR D ET AL., NATURE, vol. 435, 2 June 2005 (2005-06-02), pages 642 - 651
MAHFOUZ, MAGDY M ET AL., PNAS, vol. 108, no. 6, 8 February 2011 (2011-02-08), pages 2623 - 2628
JINEK M ET AL., SCIENCE, vol. 337, 17 August 2012 (2012-08-17), pages 816 - 821
KATZ ET AL., J VIROLOGY, vol. 77, 2003, pages 12266 - 12275
MOORE ET AL., EMBO J, vol. 77, 1992, pages 1973 - 1980
KOTWAL ET AL., VIROLOGY, vol. 171, 1989, pages 579 - 58
CHILD ET AL., VIROLOGY, vol. 174, 1990, pages 625 - 629
LEE ET AL., J VIROL, vol. 66, 1992, pages 2617 - 2630
ISAACS ET AL., PROC NATL ACAD SCI USA, vol. 89, 1992, pages 628 - 632
CANCER RESEARCH, vol. 67, 2007, pages 10038 - 10046
PLOS MEDICINE, vol. 4, 2007, pages e353
PLOS PATHOGENS, vol. 6, 2010, pages e1000984
CANCER RESEARCH, vol. 65, 2005, pages 9991 - 9998
GENE THERAPY, vol. 14, 2007, pages 638 - 647
SAITO I ET AL.: "Analytical Experiment Methods for Gene Introduction and Expression", 1 September 1997, YODOSHA CO., LTD., article "Experimental Medicine: The Protocol Series"
"EMBO Journal", vol. 6, 1987, article "DNA Cloning 4: Mammal System", pages: 3379 - 3384
HAMMOND JM. ET AL., JOURNAL OF VIROLOGICAL METHODS, vol. 66, no. l, 1997, pages 135 - 138
ONCOIMMUNOLOGY, vol. 5, no. 10, 2016, pages e1220467
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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