Title:
NEW PHOSPHODIESTERASE TYPE 7B
Document Type and Number:
WIPO Patent Application WO2001062940
Kind Code:
A3
Abstract:
This invention relates to newly identified polypeptides and polynucleotides encoding such polypeptides sometimes hereinafter referred to as "novel phosphodiesterase type 7b (PDE7b)", to their use in diagnostic and in identifying compounds that may be agonists, antagonists that are potentially useful in therapy, and to production of such polypeptides and polynucleotides.
More Like This:
Inventors:
KLUXEN FRANZ-WERNER (DE)
HENTSCH BERND (DE)
HENTSCH BERND (DE)
Application Number:
PCT/EP2001/001858
Publication Date:
January 31, 2002
Filing Date:
February 20, 2001
Export Citation:
Assignee:
MERCK PATENT GMBH (DE)
KLUXEN FRANZ WERNER (DE)
HENTSCH BERND (DE)
KLUXEN FRANZ WERNER (DE)
HENTSCH BERND (DE)
International Classes:
A61K31/7084; A61K35/76; A61K38/00; A61K39/00; A61K39/395; A61P9/00; A61P11/06; A61P29/00; G01N33/50; A61P37/02; A61P37/08; C07K16/40; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/16; C12N15/09; C12N15/10; C12N15/55; C12N15/62; C12Q1/02; C12Q1/44; C12Q1/68; G01N33/15; G01N33/53; G01N33/566; (IPC1-7): C12N15/55; C12N15/10; C12N15/62; C12N9/16; C07K16/40; C12Q1/44; G01N33/53; C12Q1/68
Domestic Patent References:
| WO2000077226A1 | 2000-12-21 |
Foreign References:
| EP1018559A1 | 2000-07-12 |
Other References:
HETMAN J M ET AL: "Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 97, no. 1, 4 January 2000 (2000-01-04), pages 472 - 476, XP002134917, ISSN: 0027-8424
DATABASE EMBL 4 February 2000 (2000-02-04), COBLEY, V.: "Human DNA sequence from clone RP11-472E5 on chromosome 6. Contains ESTs and STSs. Contains the 3' part of the gene for high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.17, rolipram-insensitive phosphodiesterase type 7) and a novel gene.", XP002174544
SASAKI TAKASHI ET AL: "Identification of human PDE7B, a cAMP-specific phosphodiesterase", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 271, no. 3, 19 May 2000 (2000-05-19), pages 575 - 583, XP002151411, ISSN: 0006-291X
DATABASE EMBL 4 February 2000 (2000-02-04), COBLEY, V.: "Human DNA sequence from clone RP11-472E5 on chromosome 6. Contains ESTs and STSs. Contains the 3' part of the gene for high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.17, rolipram-insensitive phosphodiesterase type 7) and a novel gene.", XP002174544
SASAKI TAKASHI ET AL: "Identification of human PDE7B, a cAMP-specific phosphodiesterase", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 271, no. 3, 19 May 2000 (2000-05-19), pages 575 - 583, XP002151411, ISSN: 0006-291X
Download PDF: