Title:
NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/105771
Kind Code:
A1
Abstract:
The present invention relates to a nitrogen-containing heterocyclic derivative, and a preparation method therefor and a medical application thereof. Specifically, the present invention relates to a nitrogen-containing heterocyclic derivative represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, and use thereof as a therapeutic agent, in particular the use thereof as a TYK2 inhibitor and in the preparation of a drug for treating and/or preventing inflammatory and autoimmune diseases.
Inventors:
LI XIN (CN)
DONG PING (CN)
ZHANG ZHIGAO (CN)
CHEN YANG (CN)
ZHOU YU (CN)
LIU SUXING (CN)
HE FENG (CN)
TAO WEIKANG (CN)
DONG PING (CN)
ZHANG ZHIGAO (CN)
CHEN YANG (CN)
ZHOU YU (CN)
LIU SUXING (CN)
HE FENG (CN)
TAO WEIKANG (CN)
Application Number:
PCT/CN2021/131078
Publication Date:
May 27, 2022
Filing Date:
November 17, 2021
Export Citation:
Assignee:
JIANGSU HENGRUI MEDICINE CO (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D403/14; A61K31/44; A61K31/50; A61P29/00; A61P37/00; C07D213/74; C07D401/04; C07D401/14; C07D405/14; C07D413/14; C07D471/04; C07D487/04
Domestic Patent References:
| WO2020086616A1 | 2020-04-30 |
Foreign References:
| CN111484480A | 2020-08-04 | |||
| CN106660960A | 2017-05-10 | |||
| CN104884454A | 2015-09-02 |
Attorney, Agent or Firm:
GE CHENG & CO., LTD (CN)
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