Title:
NON-HUMAN ANIMAL MODEL OF CANCER AND METHOD FOR CONSTRUCTING SAME, CANCER STEM CELL AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2016/170938
Kind Code:
A1
Abstract:
Provided is a non-human animal model of cancer that is constructed by transplanting a cancer stem cell, said cancer stem cell having characteristics of an organ or tissue, into a non-human mammal so as to induce cancer of the organ or tissue therein.
Inventors:
SENO MASAHARU (JP)
KASAI TOMONARI (JP)
IWASAKI YOSHIAKI (JP)
OHARA TOSHIAKI (JP)
HIROHATA SATOSHI (JP)
KAKUTA HIROKI (JP)
KASAI TOMONARI (JP)
IWASAKI YOSHIAKI (JP)
OHARA TOSHIAKI (JP)
HIROHATA SATOSHI (JP)
KAKUTA HIROKI (JP)
Application Number:
PCT/JP2016/060309
Publication Date:
October 27, 2016
Filing Date:
March 30, 2016
Export Citation:
Assignee:
NAT UNIV CORP OKAYAMA UNIV (JP)
International Classes:
A01K67/027; C12N5/095
Domestic Patent References:
| WO2014148562A1 | 2014-09-25 | |||
| WO1996006165A1 | 1996-02-29 | |||
| WO2013184193A2 | 2013-12-12 |
Foreign References:
| JP2014207889A | 2014-11-06 | |||
| JP2014207883A | 2014-11-06 | |||
| JP2014143954A | 2014-08-14 | |||
| US20020168763A1 | 2002-11-14 |
Other References:
CHEN LING ET AL.: "A Model of Cancer Stem Cells Derived from Mouse Induced Pluripotent Stem Cells", PLOS ONE, vol. 7, no. 4, e33544, 2012, pages 2 - 7, XP055281025
TOMONARI KASAI ET AL.: "A Model of Cancer Stem Cells Derived from Mouse iPS Cells", CELL TECHNOLOGY, vol. 32, no. 3, 2013, pages 330 - 337, XP055281025
MIZUTANI A. ET AL.: "Generation of Cancer Stem Cell Model from Mouse iPS Cells", MOLECULAR BIOLOGY OF THE CELL, vol. 22, no. 24, 2011, XP055316683, ISSN: 1059-1524
CHEN LING ET AL.: "A model of cancer stem cell line derived from mouse induced pluripotent stem cell", DAI 69 KAI PROCEEDINGS OF THE JAPANESE CANCER ASSOCIATION, 2010, pages 492, XP055281022
MASAHARU SENO ET AL.: "Mouse iPS Saibo kara Juritsu shita Gan Kansaibo Model", THE 34TH ANNUAL MEETING OF THE MOLECULAR BIOLOGY SOCIETY OF JAPAN KOEN YOSHISHU, 2011, pages 1W8pII - 6
YUKI HIRAMOTO ET AL.: "Gan Kansaibo Niche ni Okeru Gan Kansaibo no Jiko Fukusei Seigyo Kiko no Kaiseki", THE 37TH ANNUAL MEETING OF THE MOLECULAR BIOLOGY SOCIETY OF JAPAN KOEN YOSHISHU, 2014, pages 1P-0830
HIROAKI SAKUMA(FUJIMORI ET AL., JOURNAL OF JAPANESE BIOCHEMICAL SOCIETY, 2008, pages 4T19 - 11
HIDEYUKI SAYA ET AL.: "Self-renewal capacity learned from cancer stem cell analysis", REGENERATIVE MEDICINE, vol. 9, no. 2, 2010, pages 229 - 233
NOBU OSHIMA ET AL.: "Application of iPSC Technology to Cancer Treatment", JPN. J. CANCER CHEMOTHER., vol. 42, no. 2, February 2015 (2015-02-01), pages 139 - 143
TOMONARI KASAI ET AL.: "A Model of Cancer Stem Cells Derived from Mouse iPS Cells", CELL TECHNOLOGY, vol. 32, no. 3, 2013, pages 330 - 337, XP055281025
MIZUTANI A. ET AL.: "Generation of Cancer Stem Cell Model from Mouse iPS Cells", MOLECULAR BIOLOGY OF THE CELL, vol. 22, no. 24, 2011, XP055316683, ISSN: 1059-1524
CHEN LING ET AL.: "A model of cancer stem cell line derived from mouse induced pluripotent stem cell", DAI 69 KAI PROCEEDINGS OF THE JAPANESE CANCER ASSOCIATION, 2010, pages 492, XP055281022
MASAHARU SENO ET AL.: "Mouse iPS Saibo kara Juritsu shita Gan Kansaibo Model", THE 34TH ANNUAL MEETING OF THE MOLECULAR BIOLOGY SOCIETY OF JAPAN KOEN YOSHISHU, 2011, pages 1W8pII - 6
YUKI HIRAMOTO ET AL.: "Gan Kansaibo Niche ni Okeru Gan Kansaibo no Jiko Fukusei Seigyo Kiko no Kaiseki", THE 37TH ANNUAL MEETING OF THE MOLECULAR BIOLOGY SOCIETY OF JAPAN KOEN YOSHISHU, 2014, pages 1P-0830
HIROAKI SAKUMA(FUJIMORI ET AL., JOURNAL OF JAPANESE BIOCHEMICAL SOCIETY, 2008, pages 4T19 - 11
HIDEYUKI SAYA ET AL.: "Self-renewal capacity learned from cancer stem cell analysis", REGENERATIVE MEDICINE, vol. 9, no. 2, 2010, pages 229 - 233
NOBU OSHIMA ET AL.: "Application of iPSC Technology to Cancer Treatment", JPN. J. CANCER CHEMOTHER., vol. 42, no. 2, February 2015 (2015-02-01), pages 139 - 143
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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