Title:
NON-SPECIFIC REACTION INHIBITION METHOD FOR CONTINUOUS IMMUNOASSAY OF SUBSTANCE TO BE MEASURED IN SPECIMEN
Document Type and Number:
WIPO Patent Application WO/2013/080937
Kind Code:
A1
Abstract:
Provided is a non-specific reaction inhibition method which renders possible the accurate measurement of a substance to be measure in a specimen, in the continuous immunoassay of specimens including plasminogen and fibrin, said continuous immunoassay being conducted using an automated analyzer in which a specimen sampling nozzle and a measurement-reagent sampling nozzle are used in conjunction. The non-specific reaction inhibition method is characterized in that a reaction between a substance to be measured and an antibody bound to the substance to be measured is conducted in the presence of casein and tissue plasminogen activator, in the continuous immunoassay of the substance to be measured in a specimen, said continuous immunoassay using specimens including plasminogen and fibrin and being implemented by an automated analyzer in which a specimen sampling nozzle and a measurement-reagent sampling nozzle are used in conjunction. This non-specific reaction inhibition method is effective in the clinical diagnosis of diseases such as liver cancer.
Inventors:
KUSANO MASAYOSHI
YAMAMOTO HIROKO
NAGAI GO
MORITA KAZUKI
YAMAMOTO HIROKO
NAGAI GO
MORITA KAZUKI
Application Number:
PCT/JP2012/080538
Publication Date:
June 06, 2013
Filing Date:
November 27, 2012
Export Citation:
Assignee:
KYOWA MEDEX CO LTD (JP)
International Classes:
G01N33/531; G01N33/53
Foreign References:
| JP2000146954A | 2000-05-26 | |||
| JPH01217266A | 1989-08-30 | |||
| JPH05322891A | 1993-12-07 | |||
| JPS6252466A | 1987-03-07 | |||
| JPS63181861U | 1988-11-24 |
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Claims: