Title:
NOVEL BIPHENYL DERIVATIVE COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/231262
Kind Code:
A1
Abstract:
The present invention provides a novel biphenyl derivative compound or a pharmaceutically acceptable salt thereof. A biphenyl derivative compound or a pharmaceutically acceptable salt thereof, according to the present invention, is a substance for enhancing Nm23-H1/NDPK activity and can inhibit metastasis and growth of cancer, thereby exhibiting excellent effects not only in prevention, improvement, and treatment of cancer, but also in inhibition of metastasis of cancer.
Inventors:
LEE KONG JOO (KR)
LEE HEE-YOON (KR)
LEE JE JIN (KR)
KIM HWANG SUK (KR)
SEO JI-WAN (KR)
LEE HONGSOO (KR)
SHIN JI SOO (KR)
KIM BO-KYUNG (KR)
LEE HEE-YOON (KR)
LEE JE JIN (KR)
KIM HWANG SUK (KR)
SEO JI-WAN (KR)
LEE HONGSOO (KR)
SHIN JI SOO (KR)
KIM BO-KYUNG (KR)
Application Number:
PCT/KR2019/006519
Publication Date:
December 05, 2019
Filing Date:
May 30, 2019
Export Citation:
Assignee:
UNIV EWHA IND COLLABORATION (KR)
International Classes:
C07C43/205; A23L33/10; A61K31/05; A61P35/00
Domestic Patent References:
| WO2014170706A1 | 2014-10-23 | |||
| WO1997035024A1 | 1997-09-25 |
Foreign References:
| CN103980153A | 2014-08-13 |
Other References:
XI, J. ET AL.: "Efficient Synthesis of Phenanthridines Using Hendrickson Reagent Initiated Cascade Reaction under Mild Conditions", SYNLETT., vol. 11, 2010, pages 1674 - 1678, XP055659822
HORI, M. ET AL.: "Dibenzothiophenes and Related Compounds. IV. Reactions of 5-Substituted 10, 11-Dihydrodibenzo [b, f] thiepinium Salts with Aryllithiums", CHEMICAL AND PHARMACEUTICAL BULLETIN, vol. 22, 1974, pages 2014 - 2019, XP055659825
RYOTA WAKABAYASHI, TAKUYA KURAHASHI, SEIJIRO MATSUBARA: "Synthesis of Phenanthrenes by Cationic Chromium(III) Porpbyrin-Catalyzed Dehydration Cycloaromatization", SYNLETT, vol. 24, no. 17, 23 September 2013 (2013-09-23), pages 2297 - 2301, XP055763149, ISSN: 0936-5214, DOI: 10.1055/s-0033-1339710
"Remington's Pharmaceutical Science", MACK PUBLISHING COMPANY
See also references of EP 3805192A4
HORI, M. ET AL.: "Dibenzothiophenes and Related Compounds. IV. Reactions of 5-Substituted 10, 11-Dihydrodibenzo [b, f] thiepinium Salts with Aryllithiums", CHEMICAL AND PHARMACEUTICAL BULLETIN, vol. 22, 1974, pages 2014 - 2019, XP055659825
RYOTA WAKABAYASHI, TAKUYA KURAHASHI, SEIJIRO MATSUBARA: "Synthesis of Phenanthrenes by Cationic Chromium(III) Porpbyrin-Catalyzed Dehydration Cycloaromatization", SYNLETT, vol. 24, no. 17, 23 September 2013 (2013-09-23), pages 2297 - 2301, XP055763149, ISSN: 0936-5214, DOI: 10.1055/s-0033-1339710
"Remington's Pharmaceutical Science", MACK PUBLISHING COMPANY
See also references of EP 3805192A4
Attorney, Agent or Firm:
SON, Min (KR)
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