Title:
NOVEL COMPOUND
Document Type and Number:
WIPO Patent Application WO/2014/136786
Kind Code:
A1
Abstract:
The invention provides novel substances that exhibit anti-tumor activity and are set forth in one of the following formulas. (‒)‒(3R)‒3"‒hydroxy‒4"‒O‒methyl nyasol (1) (compound (1)), the enantiomer thereof, and a derivative having compound (1) or the enantiomer thereof as a core structure. (‒)‒(3R)‒3'‒hydroxy‒4'‒O‒methyl nyasol (2) (compound (2)) and a derivative having compound (2) as a core structure.
Inventors:
MIYAMOTO TOMOFUMI (JP)
YAZAKI RYO (JP)
YAZAKI RYO (JP)
Application Number:
PCT/JP2014/055496
Publication Date:
September 12, 2014
Filing Date:
March 04, 2014
Export Citation:
Assignee:
UNIV KYUSHU NAT UNIV CORP (JP)
International Classes:
C07C43/23; A61K31/085; A61P35/00
Foreign References:
| KR100856335B1 | 2008-09-04 | |||
| JPS61127763A | 1986-06-16 |
Other References:
HONG-JIE ZHANG ET AL.: "Bioactive Constituents from Asparagus cochinchinensis", JOURNAL OF NATURAL PRODUCTS, vol. 67, no. 2, 2004, pages 194 - 200, XP002629732, DOI: doi:10.1021/NP030370B
D. D. SOEJARTO ET AL.: "An ethnobotanical survey of medicinal plants of Laos toward the discovery of bioactive compounds as potential candidates for pharmaceutical development", PHARMACEUTICAL BIOLOGY, vol. 50, no. 1, 2012, pages 42 - 60
KAREN DU TOIT ET AL.: "Anti-inflammatory activity and QSAR studies of compounds isolated from Hyacinthaceae species and Tachiadenus longiflorus Griseb. (Gentianaceae", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 13, no. 7, 2005, pages 2561 - 2568
D. D. SOEJARTO ET AL.: "An ethnobotanical survey of medicinal plants of Laos toward the discovery of bioactive compounds as potential candidates for pharmaceutical development", PHARMACEUTICAL BIOLOGY, vol. 50, no. 1, 2012, pages 42 - 60
KAREN DU TOIT ET AL.: "Anti-inflammatory activity and QSAR studies of compounds isolated from Hyacinthaceae species and Tachiadenus longiflorus Griseb. (Gentianaceae", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 13, no. 7, 2005, pages 2561 - 2568
Attorney, Agent or Firm:
HAMADA Yuriko et al. (JP)
Yuriko Hamada (JP)
Yuriko Hamada (JP)
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