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Title:
NOVEL PEPTIDE DERIVATIVE DERIVED FROM ADIPONECTIN AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/106897
Kind Code:
A1
Abstract:
The present invention relates to a novel peptide derivative, etc., the peptide derivative being a partially modified adiponectin receptor peptide which, compared to conventional adiponectin receptor peptides, has higher stability, superior p-AMPK activity, and improved physical properties and activity and thus offers advantages when formulated into a drug. Therefore, the peptide derivative of the present invention can be used to prevent or treat inflammatory skin diseases, wounds, hair loss, fibrosis, metabolic diseases, or cancer, to prevent or alleviate aging, sensitive skin, or wrinkles, or to enhance moisturization.

Inventors:
CHUNG JIN HO (KR)
KIM EUN JU (KR)
SUH JOONG HEON (KR)
LEE JI HOON (KR)
KWAK YOON NA (KR)
JUNG GO NI (KR)
PARK SUN YOU (KR)
CHOI MYEONG A (KR)
MIN JU SIK (KR)
LEE HA YEON (KR)
Application Number:
PCT/KR2022/020076
Publication Date:
June 15, 2023
Filing Date:
December 09, 2022
Export Citation:
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Assignee:
SEOUL NAT UNIV HOSPITAL (KR)
DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR)
International Classes:
C07K5/113; A61K8/64; A61K38/00; A61P3/00; A61P17/00; A61P35/00; A61Q17/00; C07K7/06; C07K14/47
Domestic Patent References:
WO2020050428A12020-03-12
Foreign References:
KR101915386B12018-11-08
KR20150032401A2015-03-26
Other References:
DATABASE REGISTRY 20 December 2012 (2012-12-20), ANONYMOUS : "L-Phenylalanine, glycyl-L -histidyl-L-phenylala nyl-L-phenylalanyl", XP093070824, retrieved from STN Database accession no. 1415263-18-1
DATABASE REGISTRY 9 August 2002 (2002-08-09), ANONYMOUS : "L-Lysine, glycyl-L-isoleuc yl-L-tyrosyl-L-phenyl alanyl- (9CI) (CA IND EX NAME)", XP093070832, retrieved from STN Database accession no. 443301-50-6
Attorney, Agent or Firm:
MUHANN PATENT & LAW FIRM (KR)
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