Title:
A NOVEL POLYPEPTIDE-G-PROTEIN ACTIVATING PROTEIN 129 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE
Document Type and Number:
WIPO Patent Application WO/2001/029075
Kind Code:
A1
Abstract:
The invention discloses a newly identified polypeptide which is namely G-protein activating protein 129 and the polynucleotide encoding said polypeptide and a process for producing them by recombinant methods. The invention also discloses that the polypeptide could be used for the treatment of various kinds of diseases, such as cancer, immune disease, metabolic disorder, hypogenesis and visual disturbance. The antagonist of the polypeptide and the therapeutic use of the same is also disclosed. In addition, it refers to the use of the polynucleotide encoding said polypeptide 129.
Inventors:
MAO YUMIN (CN)
XIE YI (CN)
XIE YI (CN)
Application Number:
PCT/CN2000/000329
Publication Date:
April 26, 2001
Filing Date:
October 16, 2000
Export Citation:
Assignee:
SHANGHAI BIO ROAD GENE DEV LTD (CN)
MAO YUMIN (CN)
XIE YI (CN)
MAO YUMIN (CN)
XIE YI (CN)
International Classes:
C07K14/47; A61K38/00; (IPC1-7): C07K14/435; A61K38/17
Other References:
BHATTACHARYA D. ET AL.: "Molecular phylogenetic analysis of actin genic regions from achly bisexualis (oomycota) and costaria costata (chromophyta)", J. MOL. EVOL., vol. 33, no. 6, 1991, pages 525 - 536
Attorney, Agent or Firm:
SHANGHAI HUA DONG PATENT AGENCY (319 Yue Yang Road Shanghai 1, CN)
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